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Well-differentiated (oncocytoid) neuroendocrine carcinoma of the larynx with multiple skin metastases: a brief report

Published online by Cambridge University Press:  29 June 2007

U. Schmidt ,
K. A. Metz ,
M. Schrader  and
L.-D. Leder
U. Schmidt*
Affiliation:
Institute of Pathology, University of Essen, Germany.
K. A. Metz
Affiliation:
Institute of Pathology, University of Essen, Germany.
M. Schrader
Affiliation:
Institute Department of Otorhinolaryngology, University of Essen, Germany
L.-D. Leder
Affiliation:
Institute of Pathology, University of Essen, Germany.
*
Dr U. Schmidt, Institute of Pathology, University of Essen, Hufelandstr. 55, D-45122, Essen, Germany. Fax: 0201/723-5926
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Abstract

A 63-year-old woman presented with a history of increasing dysphagia of about two weeks duration. Laryngoscopy revealed a nonulcerated supraglottic epitheliomatous lesion that morphologically appeared well-differentiated and distinctly oncocytoid. Although the tumour lacked any criteria for malignancy such as cellular atypia, pleomorphism or necroses, it recurred twice after primary surgery and later gave rise to multiple painful skin metastases. The diagnosis of an oncocytoid differentiated neuroendocrine carcinoma of the larynx (laryngeal carcinoid) was made. Misinterpretation of laryngeal carcinoids is common, but can be avoided if one is familiar with this rare variant of laryngeal neoplasms

Keywords

Laryngeal neoplasmsCarcinoid tumour
Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 108 , Issue 3 , March 1994 , pp. 272 - 274
Copyright
Copyright © JLO (1984) Limited 1994

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References

Blok, P. H. H. M., Manni, J. J., van Haelst, U. J. G. M., van den Broek, P., Sloof, J. L. (1985) Carcinoid of the larynx: a report of three cases and a review of the literature. Laryngoscope 95: 715–719.CrossRefGoogle Scholar
El Naggar, A. K., Batsakis, J. G., Vassilopoulou-Sellin, R., Ordonez, N. G., Luna, M. A. (1991) Medullary (thyroid) carcinoma-like carcinoids of the larynx. Journal of Laryngology and Otology 105: 683–686.CrossRefGoogle ScholarPubMed
Ferlito, A., Friedmann, I., Goldman, N. C. (1988) Primary carcinoid tumour of the larynx. Journal of Oto-Rhino-Laryngology and its related Specialities 50: 129–149.CrossRefGoogle ScholarPubMed
Ferlito, A., Friedmann, I. (1989) Review of neuroendocrine carcinomas of the larynx. Annals of Otology. Rhinology and Laryngology 98: 780–790.CrossRefGoogle Scholar
Ferlito, A., Rosai, J. (1991) Terminology and classification of neuroendocrine neoplasms of the larynx. Journal of Oto-Rhino-Laryngology and its related Specialties 53: 185–187.CrossRefGoogle ScholarPubMed
Stanley, R. J., DeSanto, L. W., Weiland, L. H. (1986) Oncocytic and oncocytoid carcinoid tumors (well-differentiated neuroendocrine carcinomas) of the larynx. Archives of Otolaryngology, Head and Neck Surgery 112: 529–535.CrossRefGoogle ScholarPubMed
Wenig, B. M., Hyams, V. J., Heffner, D. K. (1988) Moderately differentiated neuroendocrine carcinoma of the larynx. Cancer 62: 2658–2676.3.0.CO;2-M>CrossRefGoogle ScholarPubMed
Woodruff, J. M., Senie, R. T. (1991) Atypical carcinoid tumor of the larynx. Journal of Oto-Rhino-Laryngology and its related Specialties 53: 194–209.CrossRefGoogle ScholarPubMed