Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-28T00:00:08.295Z Has data issue: false hasContentIssue false
  • English
  • Français

Twelve cases of glottic carcinoma in situ treated by radiotheraphy: an observation on clinical course versus response

Published online by Cambridge University Press:  29 June 2007

J. P. Brooks ,
D. W. Morgan  and
J. Glaholm
J. P. Brooks
Affiliation:
Department of Otolaryngology, East Birmingham Hospital, 45 Bordesley Green East, Birmingham B9 5ST
D. W. Morgan
Affiliation:
Department of Otolaryngology, East Birmingham Hospital, 45 Bordesley Green East, Birmingham B9 5ST
J. Glaholm*
Affiliation:
Department of Radiotheraphy, Birmingham Oncology Centre, Queen Elizabeth Hospital, Edgbaston, Birmingham
*
Dr J. Glaholm, Birmingham Oncology Centre, Queen Elizabeth Hospital, Birmingham B15 2TH
Get access Rights & Permissions [Opens in a new window]

Abstract

Carcinoma in Situ (CIS) of the glottis is an uncommon and poorly understood condition with few, large, long- term studies. Twelve cases are presented which were treated with radiotherapy. At three-year follow-up all the patients are disease free and in 83 per cent the mucosa has returned to normal. The alternative methods of treatment are discussed.

Keywords

Laryngeal neoplasmsCarcinoma in situRadiotherapy
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 11 , November 1993 , pp. 1014 - 1016
Copyright
Copyright © JLO (1984) Limited 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Auerbach, O., Hammond, E. D., Garfinkel, L. (1970) Histological changes in the larynx in relation to smoking habits. Cancer 25: 92–104.3.0.CO;2-E>CrossRefGoogle ScholarPubMed
Bauer, W. C., McGavran, M. H. (1972) Carcinoma in situ and evaluation of epithelial changes in laryngopharyngeal biopsies. Journal of the American Medical Association 221: 72–74.CrossRefGoogle ScholarPubMed
Chacko, D. C., Hendrickson, E. R., Fisher, A. (1983) Definitive irradiation of Tl-T4NO larynx cancer. Cancer 51: 994–1000.3.0.CO;2-F>CrossRefGoogle ScholarPubMed
Doyle, R. J., Flores, A., Douglas, G. S. (1977) Carcinoma in situ of the larynx. Laryngoscope 87: 310–316.CrossRefGoogle ScholarPubMed
Eckel, H. E., Thumfart, W. F. (1992) Laser surgery for the treatment of larynx carcinomas: indications, techniques and preliminary results. Annals of Otology, Rhinology and Lwyngology 101: 113–118.CrossRefGoogle ScholarPubMed
Elner, A., Fex, S. (1988) Carbon dioxide laser as primary treatment of glottic T1S and T1A tumours. Acta Otolaryngologica 449: 135–139.CrossRefGoogle ScholarPubMed
Fernberg, J. O., Ringborg, U., Silfversward, C., Ewert, G., Haglund, S., Schiratzki, H. (1989) Radiation therapy in early glottic cancer: analysis of 177 consecutive cases. Acta Otolaryngologica 108: 478–481.CrossRefGoogle ScholarPubMed
Fletcher, G. H., Lindberg, R. D., Hamberger, A., Horiot, J. C. (1975) Reasons for irradiation failure in squamous cell carcinoma of the larynx. Laryngoscope 85: 987–1003.CrossRefGoogle ScholarPubMed
Garrett, M. (1959) Eight further cases of radiation-induced cancer. British Medical Journal 23: 1329–1331.CrossRefGoogle Scholar
Glaubiger, D. L., Caslor, J. A., Garrett, W. L., Yoo, H. S., Lillis-Hearne, P. K. (1991) Chondrosarcoma of the larynx after radiation treatment for vocal cord cancer. Cancer 68 (8): 1828–1831.3.0.CO;2-L>CrossRefGoogle ScholarPubMed
Hintz, B. L., Kagan, A. R., Nussbaum, H., Rao, A. R., Chau, P. Y. M., Miles, J. (1981) A ‘Watchful Waiting’ policy for in situ carcinoma of the vocal cords. Archives of Otolaryngology 107: 746–751.CrossRefGoogle ScholarPubMed
Hirano, M., Hirade, Y., Kawasaki, , (1985) Vocal function following carbon dioxide laser surgery for glottic carcinoma. Annals of Otology. Rhinology and Laryngology 94: 232–235.CrossRefGoogle ScholarPubMed
MacLeod, P. M., Daniel, F. (1990) The role of radiotherapy in in situ carcinoma of the larynx. International Journal of Radiation, Oncology, Biology and Physics 18: 113–117.CrossRefGoogle ScholarPubMed
McGuirt, W. F., Browne, J. D. (1991) Management decisions in laryngeal carcinoma in situ. Laryngoscope 101: 125–129.CrossRefGoogle ScholarPubMed
Olofsson, J., Franzen, G., Lundgren, J. (1986) Hypertetraploid cells in vocal cord epithelia. Clinical Otolaryngology 11: 345–351.CrossRefGoogle ScholarPubMed
Rothfield, R. E., Myers, E. N., Johnson, J. T. (1991) Carcinoma in situ and microinvasive squamous cell carcinoma of the vocal cords. Annals of Otology, Rhinology and Laryngology 100: 793–796.CrossRefGoogle ScholarPubMed
Shvero, J., Hadar, T., Segal, K., Abraham, A., Sidi, J. (1988) Carcinoma in Situ of the vocal cords. A retrospective study. Clinical Otolaryngology 13: 235–237.CrossRefGoogle ScholarPubMed
Stenersen, T. C., Hoel, P. S., Boysen, M. (1988) Carcinoma in Situ of the larynx. Results with different methods of treatment. Acta Otolaryngologica 449: 131–133.CrossRefGoogle ScholarPubMed
Stenersen, T. C., Hoel, P. S., Boysen, M. (1991) Carcinoma in situ of the larynx: an evaluation of its natural clinical course. Clinical Otolaryngology 16: 358–363.CrossRefGoogle ScholarPubMed
Strong, M. S., Jako, G. J. (1972) Laser surgery in the larynx. Early clinical experience with continuous CO2 laser. Annals of Otology, Rhinology and Laryngology 81: 791–798.CrossRefGoogle Scholar
Wolfensberger, M., Don, J. C. (1990) Endoscopic laser surgery for early glottic carcinoma: a clinical and experimental study. Laryngoscope 100: 1100–1105.CrossRefGoogle ScholarPubMed