Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-24T17:51:56.188Z Has data issue: false hasContentIssue false

Submucosal glands after maxillary sinus surgery. An experimental study in rabbits

Published online by Cambridge University Press:  29 June 2007

Pablo J. Melgarejo-Moreno*
Affiliation:
Department of Otolaryngology, School of Medicine, Hospital Arnau de Vilanova, Lleida, Spain
Inmaculada Ribera-Cortada
Affiliation:
Department of Surgery, Walsall Manor Hospital, Birmingham, UK
Diego Hellin-Meseguer
Affiliation:
Department of Otolaryngology, Hospital de la Vega Baja Orihuela, Alicante, Spain
*
Address for correspondence: Dr Pablo Melgarejo-Moreno, Avda. Juan Jose Marco Banegas, 2, 30600 Archena-Murcia, Spain.

Abstract

Thirty New Zealand White rabbits underwent unilateral partial or complete removal of maxillary sinus mucosa in order to evaluate submucosal maxillary sinus glands. After three months, specimens were taken for examination from all operated on and control sinuses. Bacteriological cultures, light and electron microscopy were performed. Histopathological findings showed a decrease in the number of serous glands and significant inflammation was present in the sinus in which there was complete surgical removal. Electron microscopy revealed changes in the secretory cells of the serous glands in the regenerated postsurgical mucosa.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Benninger, M. S., Sebek, B. A., Levine, H. L. (1989) Mucosal regeneration of the maxillary sinus after surgery. Otolaryngology –Head and Neck Surgery 101: 3337.CrossRefGoogle ScholarPubMed
Benninger, M. S., Schmidt, J. L., Crissman, J. D. (1991) Mucociliary function following sinus mucosal regeneration. Otolaryngology – Head and Neck Surgery 105: 641648.Google Scholar
Forsgren, K., Kumlien, J., Stierna, P., Carlsöö, B. (1993) Regeneration of maxillary sinus mucosa following surgical removal. Experimental study in rabbits. Annals of Otology, Rhinology and Laryngology 102: 459468.CrossRefGoogle ScholarPubMed
Forsgren, K., Fukarami, M., Kumlien, J., Penttilä, M., Stierna, P. (1995) Endoscopic and Caldwell-Luc approaches in chronic maxillary sinusitis: a comparative histopathologic study on preoperative and postoperative mucosal morphology. Annals of Otology, Rhinology and Laryngology 104: 350357.CrossRefGoogle Scholar
Friedmann, C., Osborn, D. A. (1982)Pathology of Granulomas and Neoplasms of the Nose and Paranasal Sinuses. Churchill Livingstone, London, pp811.Google Scholar
Friedman, M., Toriumi, D. M. (1989) The effect of a temporary nasoantral window on mucociliary clearance. An experimental study. Otolaryngology Clinics of North America 22: 819830.CrossRefGoogle ScholarPubMed
Johansson, P., Kumlien, J., Soderlund, K., Hultman, E. (1988) Experimental acute sinusitis in rabbits. Energy metabolism in sinus mucosa and secretion. Acta Otolaryngologica (Stockholm) 106: 460467.Google Scholar
Kelemen, O. (1955) The nasal and paranasal cavities of the rabbit in the experimental work. Archives of Otolaryngology 61: 497512.Google Scholar
Kennedy, D. W., Shaalan, H. (1989) Re-evaluation of the maxillary sinus surgery: Experimental study in rabbits. Annals of Otology, Rhinology and Laryngology 98: 901906.Google Scholar
Lund, V. J. (1988) Inferior meatal antrostomy. Fundamental considerations of design and function. Journal of Laryngology and Otology (Suppl)15:118.CrossRefGoogle ScholarPubMed
Miyaguchi, M., Uda, H., Sakai, S. (1990) Na/K-ATPase in rabbit paranasal sinus mucosa during induced sinusitis. European Archives of Oto-Rhino-Laryngology 248: 119122.Google Scholar
Ohashi, Y., Nakai, Y. (1983) Functional and morphological pathology of chronic sinusitis mucous membrane. Acta Otolaryngologica (Stockholm) (Suppl) 397: 1118.CrossRefGoogle ScholarPubMed
Ohashi, Y., Nakai, Y., Ikeoka, H., Furuya, H. (1991) Regeneration of nasal mucosa following mechanical injury. Acta Otolaryngologica (Stockholm) (Suppl)486: 193201.Google Scholar
Perko, D., Karin, R. R. (1992) Nasoantral windows: an experimental study in rabbits. Laryngoscope 102: 320326.Google Scholar
Petruson, B. (1994) Secretion from gland and globet cells in infected sinuses. Acta Otolaryngologica (Stockholm) (Suppl)515: 3337.Google Scholar
Taylor, M. (1992) Physiology of the nose and paranasal sinuses. In Otolaryngology. Vol 2 (English, G. M., ed.) J. B. Lippincott Company, Philadelphia, pp175Google Scholar
Toppozada, H. M., Talaat, M. A. (1980) The normal human maxillary sinus mucosa. An electron microscopic study. Acta Otolaryngologica (Stockholm) 89: 204213.Google Scholar
Tos, M. (1982)Goblet cells and glands in the nose and paranasal sinuses. In The Nose. Upper Airway Physiology and the Atmospheric Environment.1st Edition. (Proctor, D. F., Andersen, I., eds.)Elsevier Biomedical Press,Amsterdam, pp99144.Google Scholar
Tos, M., Mogensen, C. (1984) Mucus production in chronic maxillary sinusitis. A quantitative histopathological study. Acta Otolaryngologica (Stockholm) 97: 151159.Google Scholar
Stammberger, H. (1986) Endoscopic endonasal surgeryconcepts in treatment of recurring rhinosinusitis. Part I. Anatomic and pathophysiologic considerations. Otolaryngology –Head and Neck Surgery 94: 143147.Google Scholar
Westrin, K. M. Carlsöö, B., Stierna, P., Hellström, S. (1993) Mucosal fine structure in experimental sinusitis. Annals of Otology, Rhinology and Laryngology 102: 639645.Google Scholar