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Studying the result of underlay myringoplasty using platelet-rich plasma

Published online by Cambridge University Press:  29 October 2018

S P S Yadav ,
J S Malik ,
P Malik ,
P K Sehgal ,
J S Gulia  and
R K Ranga
S P S Yadav
Affiliation:
Department of Otolaryngology, Post-Graduate Institute of Medical Sciences (‘PGIMS’), Rohtak, India
J S Malik
Affiliation:
Department of Otolaryngology, Post-Graduate Institute of Medical Sciences (‘PGIMS’), Rohtak, India
P Malik*
Affiliation:
Department of Otolaryngology, Post-Graduate Institute of Medical Sciences (‘PGIMS’), Rohtak, India
P K Sehgal
Affiliation:
Department of Blood Transfusion, Post-Graduate Institute of Medical Sciences (‘PGIMS’), Rohtak, India
J S Gulia
Affiliation:
Department of Otolaryngology, Post-Graduate Institute of Medical Sciences (‘PGIMS’), Rohtak, India
R K Ranga
Affiliation:
Department of Otolaryngology, Post-Graduate Institute of Medical Sciences (‘PGIMS’), Rohtak, India
*
Author for correspondence: Dr Priya Malik, Room no. 211, Girls Hostel, PGIMS, Rohtak 124001, Haryana, India E-mail: [email protected]
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Abstract

Objective

Perforations of the tympanic membrane are treated with various surgical techniques and materials. This study aimed to determine the efficacy of platelet-rich plasma during underlay myringoplasty.

Methods

The study included 40 patients. Autologous platelet-rich plasma was applied in-between temporalis fascia graft and tympanic membrane remnant during underlay myringoplasty in group 1 (n = 20). The outcome was evaluated after three months and compared with group 2 (n = 20), a control group that underwent routine underlay tympanoplasty.

Results

After three months’ follow up, graft uptake was 95 per cent in group 1 and 85 per cent in group 2 (p < 0.03). Mean hearing threshold gain was 18.62 dB in group 1 and 13.15 dB in group 2. This difference was statistically significant (p < 0.01).

Conclusion

Platelet-rich plasma, with its ease of preparation technique, availability, low cost, autologous nature and good graft uptake rate, justifies its use in tympanoplasty type I procedures.

Keywords

Platelet-Rich PlasmaTympanoplastyOtitis Media, SuppurativeMyringoplastyPlatelet-Derived Growth Factor
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 11 , November 2018 , pp. 990 - 994
Copyright
Copyright © JLO (1984) Limited, 2018 

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Footnotes

Dr P Malik takes responsibility for the integrity of the content of the paper

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