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Published online by Cambridge University Press: 29 June 2007
An unusual squamous cell carcinoma of the larynx containing numerous multinucleated osteoclast-like giant cells in described. These cells occurred in areas of vigorous angiogenesis and haemorrhage. To our knowledge, this is the first case of laryngeal squamous cell carcinoma with osteoclast-like giant cells reported in the literature. The patient has remained alive and free of clinical disease 5 years and 4 months after the original diagnosis.