Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-12-01T01:13:33.625Z Has data issue: false hasContentIssue false
  • English
  • Français

Sinonasal blue naevus: case report and clinicopathological review

Published online by Cambridge University Press:  14 August 2013

L M Lim ,
K B Tan ,
F Petersson  and
M Thong
L M Lim
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, National University Health System, Singapore
K B Tan
Affiliation:
Department of Pathology, National University Health System, Singapore
F Petersson
Affiliation:
Department of Pathology, National University Health System, Singapore
M Thong*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, National University Health System, Singapore
*
Address for correspondence: Dr Mark Thong, NUHS Tower Block, 1E Kent Ridge Road, Singapore 119228 Fax: +65 6772 3850 E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

To highlight the important clinical and histological features of sinonasal blue naevi.

Methods:

A case of blue naevus of the nasal cavity is described (including endoscopic and histological pictures) and the existing literature is reviewed.

Results:

There have been five reported cases (including the presented case). Clinically, sinonasal blue naevi are heavily pigmented lesions that are small and asymptomatic. Histopathologically, blue naevi exhibit heavily pigmented dendritic melanocytes that are never abnormal in form.

Conclusion:

Blue naevus should be a differential diagnosis for pigmented lesions within the sinonasal cavity, despite its rarity. It may be initially suspected by its small size and asymptomatic nature. However, histological examination is required for definitive diagnosis, looking for the key microscopic features described above.

Keywords

Nevus, BlueNasal CavityDiagnosisPathology
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 9 , September 2013 , pp. 939 - 941
Copyright
Copyright © JLO (1984) Limited 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Presented at the International Rhinology Society International Symposium on Infection and Allergy of the Nose, 22 September 2011, Tokyo, Japan

References

1Prasad, ML. Update on pigmented lesions of the sinonasal tract. Head Neck Pathol 2007;1:50–4CrossRefGoogle ScholarPubMed
2Ojha, J, Akers, JL, Akers, JO, Hassanein, AM, Islam, NM, Cohen, DM et al. Intraoral cellular blue nevus: report of a unique histopathologic entity and review of the literature. Cutis 2007;80:189–92Google ScholarPubMed
3Craddock, KJ, Bandarchi, B, Khalifa, MA. Blue nevi of the Müllerian tract: case series and review of the literature. J Low Genit Tract Dis 2007;11:284–9CrossRefGoogle ScholarPubMed
4Golden, N, Maliawan, S, Mulyadi, K. Cellular blue naevus of the scalp with brain invasion. J Clin Neurosci 2000;7:453–4CrossRefGoogle ScholarPubMed
5Di Nuovo, F, Sironi, MG, Spinelli, M. True prostatic blue nevus associated with melanosis: case report, histogenesis and review of the literature. Adv Clin Path 2002;6:135–9Google ScholarPubMed
6Misago, N, Nagase, K, Toda, S, Shinoda, Y, Koba, S, Narisawa, Y. Cellular blue nevus with nevus cells in a sentinel lymph node. Eur J Dermatol 2008;18:586–9Google Scholar
7Gershtenson, PC, Krunic, A, Chen, H, Konanahalli, M, Worobec, S. Subungual and periungual congenital blue naevus. Australas J Dermatol 2009;50:144–7CrossRefGoogle ScholarPubMed
8Wang, Q, Prieto, V, Esmaeli, B, Kolda, T, Lazar, A, Ivan, D et al. Cellular blue nevi of the eyelid: a possible diagnostic pitfall. J Am Acad Dermatol 2008;58:257–60CrossRefGoogle ScholarPubMed
9Chuang, WY, Hao, SP, Yeh, CJ, Jung, SM. Blue nevi of the sinonasal mucosa: a report of two cases and review of the literature. Laryngoscope 2007;117:371–2CrossRefGoogle ScholarPubMed
10Piana, S, Asioli, S. Blue nevus of the nasal mucosa. Virchows Arch 2005;446:342–3CrossRefGoogle ScholarPubMed
11Aneiros, J, O'Valle, F, Garcia del Moral, R, Gomez Morales, M, Alvaro, T. Blue nevus of the maxillary sinus. An immunohistochemical and electron microscopic study. Acta Otorhinolaryngol Belg 1989;43:163–7Google ScholarPubMed
12Plaza, JA, Torres-Cabala, C, Evans, H, Diwan, HA, Suster, S, Prieto, VG. Cutaneous metastases of malignant melanoma: a clinicopathologic study of 192 cases with emphasis on the morphologic spectrum. Am J Dermatopathol 2010;32:129–36CrossRefGoogle ScholarPubMed
13Lee, H, Torres, FX, McLean, SA, Chen, R, Lee, MW. Immunophenotypic heterogeneity of primary sinonasal melanoma with aberrant expression of neuroendocrine markers and calponin. Appl Immunohistochem Mol Morphol 2011;19:48–53CrossRefGoogle ScholarPubMed