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Salivary duct adenocarcinoma: a high grade malignancy

Published online by Cambridge University Press:  29 June 2007

Kathleen K. Hui
Affiliation:
Department of Pathology, M.D. Anderson Hospital, Houston, Texas 77030.
John G. Batsakis*
Affiliation:
Department of Pathology, M.D. Anderson Hospital, Houston, Texas 77030.
Mario A. Luna
Affiliation:
Department of Pathology, M.D. Anderson Hospital, Houston, Texas 77030.
Bruce MacKay
Affiliation:
Department of Pathology, M.D. Anderson Hospital, Houston, Texas 77030.
Robert M. Byers
Affiliation:
Department of Head and Neck Surgery, M.D. Anderson Hospital, Houston, Texas 77030.
*
John G. Batsakis, M.D., Department of Pathology, M.D. Anderson Hospital, Houston, Texas 77030, U.S.A.

Abstract

Salivary duct carcinomas of the major salivary glands have two major distinguishing features. They closely resemble ductal carcinomas of the breast and they are high-grade malignancies. In general, but particularly for carcinomas measuring three or more centimeters in size, the clinical course is one characterized by a resistance to local control, metastases to regional lymph nodes and distant sites, and death within a few years after primary surgical treatment.

Type
Research Article
Copyright
Copyright © JLO (1984) Limited 1986

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References

Batsakis, J. G. (1980) Salivary gland neoplasia: An outcome of modified morphogenesis and cytodifferentiation. Oral Surgery, Oral Medicine, Oral Pathology, 49: 229232.CrossRefGoogle ScholarPubMed
Batsakis, J. G., Pinkston, G. R., Luna, M. A., Byers, R. M., Sciubba, J. J. and Tillery, G. W. (1983) Adenocarcinoma of the oral cavity: A clinicopathologic study of terminal duct carcinoma. Journal of Laryngology and Otology, 97: 825835.CrossRefGoogle Scholar
Corio, R. L., Sciubba, J. J., Brannon, R. B. and Batsakis, J. G. (1982) Epithelial and myoepithelial carcinoma of intercalated duct origin. Oral Surgery, Oral Medicine, Oral Pathology, 53: 280287.CrossRefGoogle ScholarPubMed
Donath, L., Seifert, G. and Schmitz, R. (1972) Zur Diagnose and Ultrastruktur des tubulären Speichelgangcarcinoms: Epithelial-myoepithelialesSchaltstückcarcinom. Virchows Archiv; A: Path Anat 356: 1631.CrossRefGoogle Scholar
Garland, T. A., Innes, D. J. and Fechner, R. E. (1984) Salivary duct carcinoma: An Analysis of four cases with review of the literature. American Journal of Clinical Pathology, 81: 436441.CrossRefGoogle Scholar
Kleinsasser, O., Klein, H. J. and Hübner, G. (1968) Speichelgangcarcinom. Eine der Milchgangcarcinomender Brustdrüse analoge Gruppe von Speicheldrüsentumoren. Archiv für Klinische und Experimented Ohren- Nasen-und Kehlkopfheikunde, 192: 100115.CrossRefGoogle Scholar
Regezi, J. A. and Batsakis, J. G. (1977) Histogenesis of salivary gland neoplasms. Otolaryngologic Clinics of North America, 10: 297307.CrossRefGoogle ScholarPubMed