Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-08T11:30:53.450Z Has data issue: false hasContentIssue false
  • English
  • Français

Retrospective analysis of the risk of neoplasia associated with unilateral maxillary sinus opacification on computed tomography

Published online by Cambridge University Press:  07 April 2022

Z Mughal Open the ORCID record for Z Mughal [Opens in a new window] ,
K Daffu ,
R Adeoti ,
R Swaminathan  and
S Henney
Z Mughal*
Affiliation:
Department of Otolaryngology, Warwick Hospital, Warwick, UK
K Daffu
Affiliation:
Department of Otolaryngology, Warwick Hospital, Warwick, UK
R Adeoti
Affiliation:
Department of Otolaryngology, Warwick Hospital, Warwick, UK
R Swaminathan
Affiliation:
Department of Otolaryngology, Warwick Hospital, Warwick, UK
S Henney
Affiliation:
Department of Otolaryngology, Warwick Hospital, Warwick, UK
*
Author for correspondence: Mr Zahir Mughal, Department of Otolaryngology, Warwick Hospital, Lakin Rd, WarwickCV34 5BW, UK E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Background

Unilateral maxillary sinus opacification on computed tomography may reflect an inflammatory or neoplastic process. The neoplasia risk is not clear in the literature.

Methods

In this retrospective study, computed tomography sinus scans performed over 12 months were screened for unilateral maxillary sinus opacification, and the rates of inflammatory and neoplastic diagnoses were calculated.

Results

Of 641 computed tomography sinus scans, the rate of unilateral maxillary sinus opacification was 9 per cent. Fifty-two cases were analysed. The risk of neoplasia was 2 per cent (inverted papilloma, n = 1). No cases of unilateral maxillary sinus opacification represented malignancy, but one case of lymphoma had an incidental finding of unilateral maxillary sinus opacification on the contralateral side. Patients with an antrochoanal polyp (n = 3), fungal disease (n = 1), inverted papilloma and lymphoma all had a unilateral nasal mass.

Conclusion

Our neoplasia rate of 2 per cent was lower than previously reported. A unilateral mass was predictive of pathology that required operative management. Clinical findings, rather than simple findings of opacification on computed tomography, should drive the decision to perform biopsy.

Keywords

Computed TomographyX-RayMaxillary SinusMaxillary SinusitisMaxillary Sinus NeoplasmsUnilateral Nasal Obstruction
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 136 , Issue 12 , December 2022 , pp. 1259 - 1264
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Mr Z Mughal takes responsibility for the integrity of the content of the paper

References

Eckhoff, A, Cox, D, Luk, L, Maidman, S, Wise, SK, DelGaudio, JM. Unilateral versus bilateral sinonasal disease: considerations in differential diagnosis and workup. Laryngoscope 2020;130:E116–2110.1002/lary.28108CrossRefGoogle ScholarPubMed
Knisely, A, Holmes, T, Barham, H, Sacks, R, Harvey, R. Isolated sphenoid sinus opacification: a systematic review. Am J Otolaryngol 2017;38:237–4310.1016/j.amjoto.2017.01.014CrossRefGoogle ScholarPubMed
Fokkens, WJ, Lund, VJ, Hopkins, C, Hellings, PW, Kern, R, Reitsma, S et al. European position paper on rhinosinusitis and nasal polyps 2020. Rhinology 2020;58(suppl S29):2–24Google ScholarPubMed
Lee, JY. Unilateral paranasal sinus diseases: analysis of the clinical characteristics, diagnosis, pathology, and computed tomography findings. Acta Otolaryngol 2008;128:621–6Google ScholarPubMed
Chen, H-J, Chen, H-S, Chang, Y-L, Huang, Y-C. Complete unilateral maxillary sinus opacity in computed tomography. J Formos Med Assoc 2010;109:709–1510.1016/S0929-6646(10)60115-5CrossRefGoogle ScholarPubMed
von Elm, E, Altman, DG, Egger, M, Pocock, SJ, Gøtzsche, PC, Vandenbroucke, JP. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 2007;370:1453–710.1016/S0140-6736(07)61602-XCrossRefGoogle ScholarPubMed
Ahsan, F, El-Hakim, H, Ah-See, KW. Unilateral opacification of paranasal sinus CT scans. Otolaryngol Head Neck Surg 2005;133:178–8010.1016/j.otohns.2005.02.010CrossRefGoogle ScholarPubMed
Chen, C-M, Su, I-H, Yeow, K-M. Unilateral paranasal sinusitis detected by routine sinus computed tomography: analysis of pathology and image findings. J Radiol Sci 2011;36:99–104Google Scholar
Kaplan, BA, Kountakis, SE. Diagnosis and pathology of unilateral maxillary sinus opacification with or without evidence of contralateral disease. Laryngoscope 2004;114:981–510.1097/00005537-200406000-00005CrossRefGoogle ScholarPubMed
Salami, AMA. Unilateral sinonasal disease: analysis of the clinical, radiological and pathological features. J Fac Med Baghdad 2009;51:372–5Google Scholar
Zahedi, FD, Mohamed, MH, Husain, S, Kew, TY, Gendeh, BS. Clinical and radiological impact markers in evaluating characteristic unilateral paranasal sinus diseases. East J Med 2018;23:258–6310.5505/ejm.2018.81300CrossRefGoogle Scholar
Rudralingam, M, Jones, K, Woolford, TJ. The unilateral opaque maxillary sinus on computed tomography. Br J Oral Maxillofac Surg 2002;40:504–710.1016/S0266-4356(02)00225-5CrossRefGoogle ScholarPubMed
Turfe, Z, Ahmad, A, Peterson, EI, Craig, JR. Odontogenic sinusitis is a common cause of unilateral sinus disease with maxillary sinus opacification. Int Forum Allergy Rhinol 2019;9:1515–2010.1002/alr.22434CrossRefGoogle ScholarPubMed
Matsumoto, Y, Ikeda, T, Yokoi, H, Kohno, N. Association between odontogenic infections and unilateral sinus opacification. Auris Nasus Larynx 2015;42:288–9310.1016/j.anl.2014.12.006CrossRefGoogle ScholarPubMed
Gâta, A, Toader, C, Valean, D, Trombitaș, VE, Albu, S. Role of endoscopic sinus surgery and dental treatment in the management of odontogenic sinusitis due to endodontic disease and oroantral fistula. J Clin Med 2021;10:271210.3390/jcm10122712CrossRefGoogle ScholarPubMed
Chua, E, Navaratnam, AV, St Leger, D, Lam, V, Unadkat, S, Weller, A. Comparison of MRI and CT in the evaluation of unilateral maxillary sinus opacification. Radiol Res Pract 2021;2021:5313196Google ScholarPubMed