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The response of adenoid cystic carcinoma to tamoxifen

Published online by Cambridge University Press:  29 June 2007

A. Shadaba ,
M. N. Gaze  and
H. R. Grant
A. Shadaba*
Affiliation:
Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK.
M. N. Gaze
Affiliation:
Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK.
H. R. Grant
Affiliation:
Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK.
*
Address for correspondence: Ms A. Shadaba, Royal National Throat, Nose and Ear Hospital, 330-332 Gray's Inn Road, London WC1X 8EE.
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Abstract

Adenoid cystic carcinoma of the parotid gland often recurs locally, or metastases develop, after initial treatment with surgery and radiotherapy. We report a patient with an inoperable local recurrence of previously irradiated adenoid cystic carcinoma, who was treated with tamoxifen, an oestrogen receptor antagonist. After 18 months of treatment with tamoxifen, MRI showed a partial response, and further clinical progression of the disease was halted.

Keywords

Parotid neoplasmsCarcinomaadenoid cysticTamoxifen
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 12 , December 1997 , pp. 1186 - 1189
Copyright
Copyright © JLO (1984) Limited 1997

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