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Research tissue banking in otolaryngology: organization, methods and uses, with reference to practical, ethical and legal issues

Published online by Cambridge University Press:  15 March 2006

M Pitchers ,
A Stokes ,
R Lonsdale ,
D J Premachandra  and
D R Edwards
M Pitchers
Affiliation:
School of Biological Sciences, University of East Anglia, Norwich
A Stokes
Affiliation:
School of Biological Sciences, University of East Anglia, Norwich
R Lonsdale
Affiliation:
Department of Histopathology
D J Premachandra
Affiliation:
Department of ENT, Norfolk and Norwich University Hospital NHS Trust, Norwich, UK
D R Edwards
Affiliation:
School of Biological Sciences, University of East Anglia, Norwich
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Abstract

The field of molecular biology is an important part of research into neoplastic conditions. Much of this research requires access to human tissue samples, which may need to be collected and stored in a specific way, according to the type of study for which they are intended. Anonymous clinical information about the samples enables researchers to apply results to different patient groups. Access to stored tissues is particularly important in head and neck disease research as many neoplastic conditions affecting this area have a relatively low incidence. Consequently, it may take a long time to build up enough individual cases to make a study worthwhile.

We describe here the current legal, ethical and practical issues of research tissue banking, with regard to head and neck disease.

Keywords

Tissue BanksHead And Neck NeoplasmsThyroid NeoplasmsGene Expression Regulations, NeoplasticMetalloproteinaseDrug Screening AssaysAntitumor
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 120 , Issue 6 , June 2006 , pp. 433 - 438
Copyright
© 2006 JLO (1984) Limited

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