Hostname: page-component-586b7cd67f-gb8f7 Total loading time: 0 Render date: 2024-11-24T14:55:48.300Z Has data issue: false hasContentIssue false

Prospective study of the use of vasoconstrictor and saline in septal surgery for infiltration

Published online by Cambridge University Press:  29 June 2007

I Vanniasegaram*
Affiliation:
(Hull)
*
I. Vanniasegaram, F.R.C.S.Ed., MaxRayne House, 109 Camden Road, London NW1 9HA.

Abstract

Vasoconstrictor agents are often used to reduce bleeding and hence improvethe operative field in surgery. These agents are potentially dangerous. A trial was undertaken to compare the use of adrenaline 1:80,000 with saline alone as an infiltrating agent in 30 consecutive patients undergoing septoplasty under general anaesthesia. This study, based on a small number of patients can draw no firm conclusions. There are no really dramatic differences between 1:80,000 adrenaline and saline, in terms of blood loss, operative time and the condition of the operative field between the two groups. However, there is a possibility that there are substantial differences, which, because of the variability of these outcomes, could not be detected in a study as small as this. It is recommended that a randomized trial involving patients is used to answer the question.

Keywords

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Johnston, M., Nisbet, H. I. A. (1961) Ventricular arrhythmias during halothane anaesthesia. British Journal of Anaesthesia, 33: 916.CrossRefGoogle Scholar
Klingenstrom, P., Nylen, B., Westermark, L. (1967) A clinical comparison between adrenaline and octapressin as vasoconstrictors in local anaesthesia. Acta Anaesthesia Scandinavia, 11: 3542.CrossRefGoogle Scholar
McClymont, L. G., Crowther, J. A. (1988) Local anaesthesia with vasconstrictor combinations in septal surgery. Journal of Laryngology, and Otology, 102: 793795.CrossRefGoogle Scholar
Millar, R. A., Gilbert, R. G. B., Brindle, G. F. (1958) Ventricular tachycardias during halothane anaesthesia. Anaesthesia,13: 164172.CrossRefGoogle Scholar
Munchow, O. B., Kurze, T. (1966) Hemostatic effectivenessof infiltration with felypressin prior to skin incisions. Journal of the American Medical Association, 196(7): 625626.CrossRefGoogle Scholar
Pfleiderer, A. G., Brockbank, M. (1988) Cocaine and adrenaline: a safe or necessary combination in the nose? A study to determine the effect of adrenaline on the absorption and adverse side effects of cocaine. Clinical Otolarygnology, 13: 421426.CrossRefGoogle ScholarPubMed