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Prognostic effect of pre- and post-admission antibiotic treatment in paediatric acute mastoiditis

Published online by Cambridge University Press:  17 October 2016

E Carmel ,
J H Curotta  and
A T Cheng
E Carmel
Affiliation:
Department of Paediatric Otolaryngology, Children's Hospital at Westmead, Sydney, Australia Sackler Faculty of Medicine, Tel Aviv University, Israel
J H Curotta
Affiliation:
Department of Paediatric Otolaryngology, Children's Hospital at Westmead, Sydney, Australia
A T Cheng*
Affiliation:
Department of Paediatric Otolaryngology, Children's Hospital at Westmead, Sydney, Australia Discipline of Child and Adolescent Health, University of Sydney, Australia
*
Address for correspondence: Dr Alan T Cheng, PO Box 610, Strathfield, NSW 2135, Australia Fax: +61 2 9763 1234 E-mail: [email protected]
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Abstract

Objective:

To evaluate the effect of pre- and post-admission antibiotic treatment in paediatric acute mastoiditis.

Design:

Retrospective study.

Method:

Eighty-eight children with acute mastoiditis, from 2003 to 2012, were studied to investigate the effect of antibiotic therapy on short and long-term sequelae.

Results:

The median period of antibiotic therapy immediately following hospital discharge was 10 days (range, 5–49 days; standard deviation = 7.46). There were no sequelae within the fortnight following antibiotic therapy completion, but 14 of 40 patients had significant sequelae thereafter, including recurrent otorrhoea, acute otitis media and ventilation tube insertion requirement. Complication rates were significantly higher among patients who had pre-admission antibiotic therapy (52 per cent), compared to patients previously untreated (27 per cent).

Conclusion:

Paediatric acute mastoiditis patients treated with antibiotic therapy prior to admission are at higher risk for complication development. The advised time period for oral antibiotic therapy following hospital discharge remains as 10 days in all cases of uncomplicated acute mastoiditis.

Keywords

MastoiditisPediatricsChildOtitis MediaAntibiotics
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 131 , Supplement S1 , January 2017 , pp. S12 - S17
Copyright
Copyright © JLO (1984) Limited 2016 

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Footnotes

Presented at the 12th International Congress of the European Society of Pediatric Otorhinolaryngology, 31 May – 3 June 2014, Dublin, Ireland.

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