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Primary non-Hodgkin's lymphoma of the larynx

Published online by Cambridge University Press:  29 June 2007

Shingo Kato ,
Mizuyoshi Sakura ,
Shoji Takooda ,
Masaharu Sakurai  and
Toshiyuki Izumo
Shingo Kato*
Affiliation:
Department of Radiotherapy, Saitama Cancer Center, Saitama, Japan.
Mizuyoshi Sakura
Affiliation:
Department of Radiotherapy, Saitama Cancer Center, Saitama, Japan.
Shoji Takooda
Affiliation:
Department of Clinics of Otolaryngology, Saitama Cancer Center, Saitama, Japan.
Masaharu Sakurai
Affiliation:
Department of Hematology, Saitama Cancer Center, Saitama, Japan.
Toshiyuki Izumo
Affiliation:
Department of Clinical Pathology, Saitama Cancer Center, Saitama, Japan.
*
Address for correspondence: Shingo Kato, M.D., Department of Radiotherapy, Saitama Cancer Center, 818 Komuro Ina-machi Kitaadachi-gun Saitama-ken 362, Japan. Fax: +81-48-723-5197
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Abstract

Three cases of primary non-Hodgkin's lymphoma of the larynx are described. Histologically, two tumours belonged to the category of low grade B-cell lymphomas of the small cell type (extranodal marginal zone B-cell lymphoma and lymphoplasmacytoid lymphoma), and the third was classified as a peripheral T-cell lymphoma of unspecified type. The clinical stage was IE in two cases, and IV in another case. In two cases, complete remission was obtained with radical radiotherapy. But in the other case, which was histologically lymphoplasmacytoid lymphoma, the response to radiotherapy was poor, and surgery was required. There was no relapse subsequent to treatment. Primary non-Hodgkin's lymphoma of the larynx is rare. Several reported cases have clinical features similar to those of MALT-type lymphomas arising in other extranodal sites. Although most of the reported cases have been cured with radiotherapy, in some cases dissemination to other extranodal sites may occur. Therefore careful periodic evaluation is imperative.

Keywords

Lymphoma, non-Hodgkin'sLarynx
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 6 , June 1997 , pp. 571 - 574
Copyright
Copyright © JLO (1984) Limited 1997

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References

Bickerton, R. C., Brockbank, M. J. (1988) Lymphoplasmacytic lymphoma of the larynx, soft palate and nasal cavity. Journal of Laryngology and Ototogy 102: 468–470.CrossRefGoogle ScholarPubMed
Desanto, L. W., Weiland, L. H. (1970) Malignant lymphoma of the larynx. Laryngoscope 80: 966–978.CrossRefGoogle ScholarPubMed
Dickson, R. (1971) Lymphoma of the larynx. Laryngoscope 81: 578–585.CrossRefGoogle ScholarPubMed
Diebold, J., Audouin, J., Viry, B., Ghandour, C., Betti, P., D'Ornano, G. (1990) Primary lymphoplasmacytic lymphoma of the larynx: A rare localization of MALT-type lymphoma. Annals of Otology, Rhinology and Laryngology 99: 577–580.CrossRefGoogle ScholarPubMed
Gregor, R. T. (1981) Laryngeal malignant lymphoma: An entity? Journal of Laryngology and Otology 95: 81–94.CrossRefGoogle ScholarPubMed
Harris, N. L., Jaffe, E. S., Stein, H., Banks, P. M., Chan, J. K. C., Cleary, M. L., Delsol, G., De Wolf-Peeters, C., Falini, B., Gatter, K. C., Grogan, T. M., Isaacson, P. G., Knowles, D. M., Mason, D. Y., Muller-Hermelink, H. -K., Pileri, S. A., Piris, M. A., Ralfkiaer, E., Warnke, R. A. (1994) A revised European-American classification of lymphoid neoplasms: A proposal from the international lymphoma study group. Blood 84: 1361–1392.CrossRefGoogle ScholarPubMed
Isaacson, P. G., Wright, D. H. (1984) Extranodal malignant lymphoma arising from mucosa-associated lymphoid tissue. Cancer 53: 2515–2524.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Jaffe, E. S., Raffeld, M., Medeiros, L. J. (1993) Histopathologic subtypes of indolent lymphomas: Caricatures of the mature B-cell system. Seminars in Oncology 20: 3–30.Google ScholarPubMed
MacKenty, J. E. (1934) Malignant disease of the larynx. Archives of Otolaryngology 20: 297–328.CrossRefGoogle Scholar
Morgan, K., MacLennan, K. A., Narula, A., Bradley, P. J., Morgan, D. A. L. (1989) Non-Hodgkin's lymphoma of the larynx (Stage IE). Cancer 64: 1123–1127.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
Siegel, R. J., Browning, D., Schwartz, D. A., Hudgins, P. A. (1992) Cytomegaloviral laryngitis and probable malignant lymphoma of the larynx in a patient with acquired immunodeficiency syndrome. Archives of Pathology and Laboratory Medicine 116: 539–541.Google Scholar
Swerdlow, J. B., Merl, S. A., Davey, F. R., Gacek, R. R., Gottlieb, A. J. (1984) Non-Hodgkin's lymphoma limited to the larynx. Cancer 53: 2546–2549.3.0.CO;2-Y>CrossRefGoogle Scholar
The non-Hodgkin's lymphoma pathologic classification project (1982). National Cancer Institute sponsored study of classifications of non-Hodgkin's lymphoma. Summary and description of a working formulation for clinical usage. Cancer 49: 2112–2135.3.0.CO;2-2>CrossRefGoogle Scholar
Wang, C. C. (1972) Malignant lymphoma of the larynx. Laryngoscope 82: 97–100.CrossRefGoogle ScholarPubMed