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Primary cervical tracheal monophasic synovial sarcoma confirmed by SYT–SSX gene rearrangement

Published online by Cambridge University Press:  31 January 2011

C E Corrales ,
G Berry  and
E J Damrose
C E Corrales
Affiliation:
Department of Otolaryngology, Stanford University, California, USA
G Berry
Affiliation:
Department of Pathology, Stanford University, California, USA
E J Damrose*
Affiliation:
Department of Otolaryngology, Stanford University, California, USA
*
Address for correspondence: Dr Edward J Damrose, Otolaryngology Department, Stanford University, 801 Welch Road, Stanford, CA 94305, USA Fax: + 1 650 725 8502 E-mail: [email protected]
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Abstract

Objective:

To review the existing diagnostic modalities and treatment for primary tracheal synovial sarcoma, and to report a case of primary cervical synovial sarcoma arising in the trachea.

Design:

Retrospective.

Setting:

Head and neck surgery unit at a tertiary university centre.

Patient:

One case of primary cervical tracheal monophasic synovial sarcoma diagnosed by SYT–SSX gene rearrangement.

Intervention:

This patient underwent surgical resection of the synovial sarcoma, together with tracheal resection and primary anastomosis assisted by laryngeal-releasing manoeuvres, without complication.

Main outcome measures:

Clinical, radiographical, pathological and surgical information were collected.

Result:

One year post-operatively, there was no evidence of recurrence.

Conclusion:

Synovial sarcoma arising in the trachea is very rare. Diagnosis is confirmed by demonstrating the SYT–SSX gene rearrangement. The first-line treatment is surgery.

Keywords

TracheaSarcomaDiagnosisPathology
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 6 , June 2011 , pp. 651 - 654
Copyright
Copyright © JLO (1984) Limited 2011

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