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Non-Hodgkin's lymphoma of the maxillary sinus in a patient with acquired immunodeficiency syndrome

Published online by Cambridge University Press:  29 June 2007

Antonio Del Forno ,
Cosmo Del Borgo ,
Adriana Turriziani ,
Fabrizio Ottaviani ,
Andrea Antinori  and
Massimo Fantoni
Antonio Del Forno
Affiliation:
Departments of Infectious Diseases, Catholic University, Rome, Italy.
Cosmo Del Borgo
Affiliation:
Departments of Infectious Diseases, Catholic University, Rome, Italy.
Adriana Turriziani
Affiliation:
Departments of Radiotherapy, Catholic University, Rome, Italy.
Fabrizio Ottaviani
Affiliation:
Departments of Otolaryngology, Catholic University, Rome, Italy.
Andrea Antinori
Affiliation:
Departments of Infectious Diseases, Catholic University, Rome, Italy.
Massimo Fantoni*
Affiliation:
Departments of Infectious Diseases, Catholic University, Rome, Italy.
*
Address for correspondence: Massimo Fantoni, M.D., Department of Infectious Diseases, Catholic University, L.go Francesco Vito 1, 00168 Rome, Italy.
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Abstract

Non-Hodgkin's lymphoma (NHL) is one of the most common malignancies in patients infected with human immunodeficiency virus (HIV); it occurs 25–60 times more frequently in HIV-infected patients than in the general population. This neoplasm in acquired immunodeficiency syndrome (AIDS) patients is a highly aggressive tumour with a poor prognosis and tends to develop in extranodal sites, such as the central nervous system, digestive tract and bone marrow. NHL involving the paranasal sinuses is rare in HIV-infected patients, and is likely to be confused clinically and radiographically with sinusitis; moreover, its optimal treatment is currently uncertain.

We present a case of NHL involving the left maxillary sinus in a patient with AIDS. The patient was treated with systemic chemotherapy (low dose-CHOP), but the malignancy did not respond. Subsequently, he was treated with local maxillary sinus irradiation which resulted in partial regression of the neoplasm and in decrease of local symptoms.

Keywords

HIVLymphoma, non-Hodgkin's
Type
Oncology in Focus
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 10 , October 1998 , pp. 982 - 985
Copyright
Copyright © JLO (1984) Limited 1998

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