Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-24T14:25:47.655Z Has data issue: false hasContentIssue false

Nasopharyngeal carcinoma in an HIV-positive patient causing severe morbidity and early death

Published online by Cambridge University Press:  29 June 2007

Jesper Hald*
Affiliation:
(Copenhagen, Denmark)
Per L. Larsen
Affiliation:
(Copenhagen, Denmark)
*
Jesper Hald, M.D., ENT University Clinic, Gentofte County Hospital, DK-2900 Hellerup, Denmark

Abstract

A nasopharyngeal carcinoma was the first event in an otherwise symptom free HIV person. No reports of simultaneous nasopharyngeal carcinoma and HIV infection are known to us. A 46-year-homosexual man was admitted to the ENT department with a three week history of pain in the throat referred to the left ear. He was found to have an irregular tumour in the nasopharynx with a lymph node metastasis to the left side of the neck. The poor response to radiotherapy and the very aggressive progress after treatment raised suspicion of a co-existing disease process. The risk of sexually transmitted HIV was confirmed post mortem and could explain the rapid progression of the tumour. No anti-HIV treatment was given concurrently with radiotherapy.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Joint Committee for cancer staging and end results reporting: Manual for staging of cancer (1978) J.B. Lippicott, Philadelphia, p. 3335.Google Scholar
Choa, G. (1991) Nasopharyngeal carcinoma. In Otolaryngology, Oncology of Head and Neck, Vol. 5 (English, G. M., ed.) J. B. Lippicott, Philadelphia, p. 135.Google Scholar
Cvitkovic, E., Bachouchi, M., Armand, J. P. (1991) Nasopharyngeal carcinoma. Biology, natural history, and therapeutic implications. HaematologylOncology Clinics of North America, Head and Neck Cancer, 5, No. 4: 821–38.Google Scholar
Myskowski, P. L., Straus, D. J., Safai, B. (1990) Lymphoma and other HIV-associated malignancies. Journal of the American Academy of Dermatology, 22: 12531260.CrossRefGoogle ScholarPubMed
Neel, H. B. (1986) Malignant neoplasms of nasopharynx. In Otolaryngology—Head and Neck Surgery. (Cummings, C. W., ed.), C. V. Mosby, St Louis, p. 399409.Google Scholar
Pichler, E., Zangerle, R., Puelacher, W., Waldhart, E., Hintner, H., Fritsch, P. (1990) AIDS–mucous membrane manifestations. Zeitschrift fur Hautkrankheit, 65: 647654.Google ScholarPubMed