Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-10T05:40:55.687Z Has data issue: false hasContentIssue false

Multiple glomus tumours

Published online by Cambridge University Press:  29 June 2007

Dimitris G. Balatsouras*
Affiliation:
Department of Otolaryngology—Head and Neck Surgery, Tzanion General Hospital of Piraeus, Greece.
Panayotis N. Eliopoulos
Affiliation:
Department of Otolaryngology—Head and Neck Surgery, Tzanion General Hospital of Piraeus, Greece.
Costas N. Economou
Affiliation:
Department of Otolaryngology—Head and Neck Surgery, Tzanion General Hospital of Piraeus, Greece.
*
Dimitris G. Balatsouras, 40-42 Charilaou Trikoupi, 18536 Piraeus, Greece.

Abstract

A patient with multiple, synchronous, non-familial head and neck paragangliomas is reported. There were three primary neoplasms, a glomus tympanicum and glomus vagale on the right side and a glomus tumour of the carotid body on the left. Such a combination has never been reported previously.

The reports of all the series with paragangliomas in the literature, as well as the reports of single cases with multiple tumours during the last three decades, are reviewed. Specific problems in diagnosis and management of multiple glomus tumours are discussed.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ahmed, A., Dodge, O. G., Kirk, R. S. (1969) Chemodectoma of the orbit. Journal of Clinical Pathology, 22: 584588.CrossRefGoogle ScholarPubMed
Alford, B. R., Guilford, F. R. (1962) A comprehensive study of tumours of the glomus jugulare. Laryngoscope, 72: 765787.CrossRefGoogle ScholarPubMed
Anderson, R., Scarcella, J. V. (1963) Carotid body tumours. American Journal of Surgery, 106: 856859.CrossRefGoogle Scholar
Azzarelli, B., Felten, S., Miyamoto, R., Muller, J., Purvin, V. (1988) Dopamine in paragangliomas of the glomus jugulare. Laryngoscope, 98: 573578.CrossRefGoogle ScholarPubMed
Baars, F. V., Van Den Broek, P., Cremers, C., Veldman, J. (1981) Familial non-chromaffinic paragangliomas (glomus tumours): Clinical aspects. Laryngoscope, 91: 988996.CrossRefGoogle ScholarPubMed
Barnes, L., Taylor, S. R. (1990) Carotid body paragangliomas: A clinico-pathologic and DNA analysis of 13 tumours. Archives of Otolaryngology—Head and Neck Surgery, 116: 447453.CrossRefGoogle Scholar
Bartels, L. J., Pennington, J., Kamerer, D. B., Browarsky, I. (1990) Primary fallopian canal glomus tumours. Otolaryngology—Head and Neck Surgery, 102: 101105.CrossRefGoogle Scholar
Bogdasarian, R. S., Lotz, P. R., Arbor, A. (1979) Multiple simultaneous paragangliomas of the head and neck in association with multiple retroperitoneal pheochromocytomas. Otolaryngology–Head and Neck Surgery, 87: 648652.CrossRefGoogle ScholarPubMed
Brown, J. S. (1985) Glomus jugulare tumours revisited: A ten-year statistical follow-up of 231 cases. Laryngoscope, 95: 284288.CrossRefGoogle ScholarPubMed
Bundgaard, T, Tandrup, O., Elbrond, O., Nordentoft, A. M. (1989) Treatment of glomus tumours: A retrospective survey. Clinical Otolaryngology, 14: 155160.CrossRefGoogle ScholarPubMed
Capps, F. C. W. (1964) Carotid body tumours and their surgical management. Proceedings of the Royal Society of Medicine, 57: 954955.Google ScholarPubMed
Chambers, R. G., Mahoney, W. D. (1968) Carotid body tumours. American Journal of Surgery, 116: 554558.CrossRefGoogle Scholar
Cole, J. M. (1979) Panel discussion: Glomus jugulare tumours of the temporal bone: Radiation of glomus tumours of the temporal bone. Laryngoscope, 89: 16231627.CrossRefGoogle ScholarPubMed
Conley, J. J. (1965) The carotid body tumour: A review of 29 cases. Archives of Otolaryngology, 81: 187193.CrossRefGoogle ScholarPubMed
Cordell, A. R., Myers, R. T, Hightower, F. (1967) Carotid body tumours. Annals of Surgery, 165: 880886.CrossRefGoogle Scholar
Davidson, J., Gullane, P. (1988) Glomus vagale tumours. Otolaryngology—Head and Neck Surgery, 99: 6670.CrossRefGoogle Scholar
Demarino, D. P., Mueller, D. P., Maves, M. D., Yuh, W. T. C., Dolan, K. D. (1990) Imaging case study of the month: Multiple paragangliomas. Annals of Otology, Rhinology and Laryngology, 99: 8586.CrossRefGoogle Scholar
Dent, T. L., Thompson, N. N., Fry, W. J. (1976) Carotid body tumours. Surgery, 80: 365372.Google Scholar
Dickinson, P. H., Griffin, S. M., Guy, A. J., McNeil, I. F. (1986) Carotid body tumour: 30 years experience. British Journal of Surgery, 73: 1416.CrossRefGoogle ScholarPubMed
Dutcher, P. O., Brackmann, D. E. (1986) Glomus tumour of the facial canal: A case report. Archives of Otolaryngology, 112: 986987.CrossRefGoogle ScholarPubMed
Endikott, J. N., Maniglia, A. J. (1980) Glomus vagale. Laryngoscope, 90: 16041611.CrossRefGoogle Scholar
Farr, H. W. (1967) Carotid body tumours: A 30 year experience at Memorial Hospital. American Journal of Surgery, 114: 614619.CrossRefGoogle Scholar
Gaylis, W., Mieny, C. G. (1977) The incidence of malignancy in carotid body tumours. British Journal of Surgery, 64: 885889.CrossRefGoogle ScholarPubMed
Glasscock, M. E., Jackson, C. G., Dickins, J. R., Wiet, R. J. (1979) Panel discussion: Glomus jugulare tumours of the temporal bone: The surgical management of glomus tumours. Laryngoscope, 89: 16401654.CrossRefGoogle Scholar
Grufferman, S., Gillman, M. W., Pasternak, L. R., Peterson, C. L., Young, W. G. (1980) Familial carotid body tumours: Case report and epidemiologic review. Cancer, 46: 21162122.3.0.CO;2-S>CrossRefGoogle ScholarPubMed
Heinrich, M. C, Harris, A. E., Bell, W. R. (1985) Metastatic intravagale paraganglioma: Case report and review of the literature. American Journal of Medicine, 78: 10171024.CrossRefGoogle Scholar
Hewitt, R.L., Ichinose, H., Weichert, R. F, Drapanas, T. (1972) Chemodectomas. Surgery, 71: 275282.Google ScholarPubMed
Hodge, K. M., Byers, R. M., Peters, L. J. (1988) Paragangliomas of the head and neck. Archives of Otolaryngology—Head and Neck Surgery, 114: 872877.CrossRefGoogle ScholarPubMed
House, J. M., Goodman, M. L., Gacek, R. R., Green, G. L. (1972) Chemodectomas of the nasopharynx. Archives of Otolaryngology, 96: 138141.CrossRefGoogle ScholarPubMed
Irons, G. B., Weiland, L. H., Brown, W. L. (1977) Paragangliomas of the neck: Clinical and pathologic analysis of 116 cases. Surgical Clinics of North America, 57: 575583.CrossRefGoogle ScholarPubMed
Irving, J. D. (1983) Angiography in the investigation of tumours of the ear: Value of digital vascular imaging. Journal of Laryngology and Otology, 97: 319331.CrossRefGoogle ScholarPubMed
Jackson, G. G., Glasscock, M. E., Harris, P. F. (1982) Glomus tumours: Diagnosis, classification and management of large lesions. Archives of Otolaryngology, 108: 401406.CrossRefGoogle ScholarPubMed
Javid, H., Chawla, S. K., Dye, W. S., Hunter, J. A., Najafi, H., Goldin, M. D., Serry, C. (1976) Carotid body tumour: Resection or reflection. Archives of Surgery, 111: 344347.CrossRefGoogle ScholarPubMed
Javid, H., Dye, W. S., Hunter, J. A., Najafi, H., Julian, O. C. (1967) Surgical management of carotid body tumour. Archives of Surgery, 95: 771779.CrossRefGoogle Scholar
Krupski, W. C. Effeney, D. J., Ehrenfeld, W. K., Stoney, R. J. (1982) Cervical chemodectoma: Technical considerations and management options. American Journal of Surgery, 144: 215220.CrossRefGoogle ScholarPubMed
Lack, E. E., Cubilla, A. L., Woodruff, J. M. (1979) Paragangliomas of the head and neck region: A pathologic study of tumours from 71 patients. Human Pathology, 10: 191218.CrossRefGoogle ScholarPubMed
Lack, E. E., Cubilla, A. L., Woodruff, J. M., Farr, H. W. (1977) Paragangliomas of the head and neck region: A clinical study of 69 patients. Cancer, 39: 397409.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Lattes, R. (1950) Nonchromaffin paraganglioma of ganglion nodosum, carotid body, and aortic-arch bodies. Cancer, 3: 667694.3.0.CO;2-I>CrossRefGoogle ScholarPubMed
Lawson, W. (1980) Glomus bodies and tumours. New York State Journal of Medicine, 80: 15671575.Google Scholar
Lees, C. D., Levine, H. L., Beven, E. G., Tucker, H. M. (1981) Tumours of the carotid body: Experience with 41 operative cases. American Journal of Surgery, 142: 362365.CrossRefGoogle ScholarPubMed
Lewis, J. S. (1983) Surgical management of tumours of the middle ear. Journal of Laryngology and Otology, 97: 299311.CrossRefGoogle ScholarPubMed
Marcuse, P. M., Chamberlin, J. A. (1956) Multicentric paragangliomas: Case report with demonstration of intravagal paraganglionic tissue at a previously undescribed level. Cancer, 9: 288292.3.0.CO;2-G>CrossRefGoogle Scholar
Mathews, F. S. (1915) Surgery of the neck. In Operative therapeusis (Johnson, A. B., ed.), Vol. 3, Appleton-Century-Crafts, Inc., New York. p. 315.Google Scholar
McGuirt, W. F, Harker, L. A. (1975) Carotid body tumours. Archives of Otolaryngology, 101: 5862.CrossRefGoogle Scholar
Mcilrath, D. C, Remine, W. H. (1963) Carotid-body tumours. Surgical Clinics of North America, 43: 11351144.CrossRefGoogle Scholar
McPherson, G. A. D., Halliday, A. W., Mansfield, A. O. (1989) Carotid body tumours and other cervical paragangliomas: Diagnosis and management in 25 patients. British Journal of Surgery, 76: 3336.CrossRefGoogle ScholarPubMed
Moore, G. R., Robbins, J. P., Sedle, D. L., Eitz-Hugh, G. S., Constable, W. C. (1973) Chemodectomas of the middle ear: A comparison of therapeutic modalities. Archives of Otolaryngology, 98: 330335.CrossRefGoogle ScholarPubMed
Morris, C. G., Balas, P. E., Cooley, D. A., Crawford, E. S., Debakey, M. E. (1963) Surgical treatment of benign and malignant carotid body tumours: Clinical experience with 16 tumours in 12 patients. American Surgeon, 29: 429437.Google Scholar
Murphy, T. P., Brackmann, D. E. (1989) Effects of preoperative embolization on glomus jugulare tumours. Laryngoscope, 99: 12441247.CrossRefGoogle Scholar
Oberman, H. A., Holtz, E, Sheffer, L. A., Majielski, J. E. (1968) Chemodectomas (nonchromaffin paragangliomas) of the head and neck: A clinicopathologic study. Cancer, 21: 838851.3.0.CO;2-M>CrossRefGoogle ScholarPubMed
Padberg, F. T., Cady, B., Persson, A. V. (1983) Carotid body tumour: The Lahey Clinic experience. American Journal of Surgery, 145: 526528.CrossRefGoogle ScholarPubMed
Parkin, J. L. (1981) Familial multiple glomus tumours and pheochromocytomas. Annals of Otology, Rhinology and Laryngology, 90: 6063.CrossRefGoogle ScholarPubMed
Pearse, A. G. E., Polak, J. M., Rost, R. W. D., Fontaine, J., Lelievre, C., LeDouarin, N. (1973) Demonstration of the neural crest origin of type I (APUD) cells in the avian carotid body, using a cytochemical marker system. Histochemie, 34: 191203.CrossRefGoogle ScholarPubMed
Phelps, P. D., Cheesman, A. D. (1990) Imaging jugulotympanic glomus tumours. Archives of Otolaryngology Head and Neck Surgery. 116: 940945.CrossRefGoogle Scholar
Phelps, P. D., Stansbie, J. M. (1988) Glomus jugulare or tympanicum?: The role of CT and MR imaging with gadolinium DTPA. The Journal of Laryngology and Otology, 102: 766776.CrossRefGoogle ScholarPubMed
Pratt, L. W. (1973) Familial carotid body tumours. Archives of Otolaryngology, 97: 334336.CrossRefGoogle Scholar
Rosen, I. B., Palmer, J. A., Goldberg, M., Mustard, R. A. (1981) Vascular problems associated with carotid body tumours. American Journal of Surgery, 142: 459463.CrossRefGoogle Scholar
Rosenwasser, H. (1945) Carotid body like tumour involving the middle ear and mastoid bone. Archives of Otolaryngology, 41: 6467.CrossRefGoogle Scholar
Rosenwasser, H. (1968) Glomus jugulare tumours: Monograph. Archives of Otolaryngology, 88: 2966.Google Scholar
Shamblin, W. R., Remine, W. H., Sheps, S. G., Harrison, E. G. (1971) Carotid body tumour (chemodectoma): Clinicopathologic analysis of 90 cases. American Journal of Surgery, 122: 732739.CrossRefGoogle Scholar
Spector, G. J., Ciralsky, R., Maisel, R. H., Ogura, J. H. (1975 a) Multiple glomus tumours in the head and neck. Laryngoscope, 85: 10661075.CrossRefGoogle ScholarPubMed
Spector, G. J., Ciralsky, R. H., Ogura, J. H. (1975 b) Glomus tumours in the head and neck: III. Analysis of clinical manifestations. Annals of Otology, Rhinology and Laryngology, 84: 7379.CrossRefGoogle ScholarPubMed
Spector, G. J., Sobol, S., Thawley, S. E., Maisel, R. H., Ogura, J. H. (1979) Panel discussion: Glomus jugulare tumours of the temporal bone: Patterns of invasion in the temporal bone. Laryngoscope, 89: 16281639.CrossRefGoogle ScholarPubMed
Staats, E. E, Brown, R. L., Smith, R. R. (1966) Carotid body tumours, benign and malignant. Laryngoscope, 76: 907916.CrossRefGoogle ScholarPubMed
Stanley, R. J., Weiland, L. H., Neel, H. B. III (1986) Pain-inducing laryngeal paraganglioma: Report of the ninth case and review of the literature. Otolaryngology—Head and Neck Surgery, 95: 107112.CrossRefGoogle ScholarPubMed
Sykes, J. M., Ossoff, R. H. (1986) Paragangliomas of the head and neck. Otolaryngologic Clinics of North America, 19: 755767.CrossRefGoogle ScholarPubMed
Van Asperen de Boer, F. R. S., Terpstra, J. L., Vink, M. (1981) Diagnosis, treatment and operative complications of carotid body tumours. British Journal of Surgery, 68: 433438.CrossRefGoogle ScholarPubMed
Vigor, W. N., Rainer, N. G., Basque, G. (1969) Cervical chemodectomas: Clinical consideration in 16 cases. American Journal of Surgery, 118: 976980.CrossRefGoogle Scholar
Werner, P. E., Crockett, H. A., McSwain, B. (1968) Malignant carotid body tumour with mandibular involvement. Oral Surgery, 25: 774789.Google ScholarPubMed
Westbrook, K. C, Guillamondegui, O. M., Medellin, H., Jesse, R. H. (1972) Chemodectomas of the neck: Selective management. American Journal of Surgery, 124: 760766.CrossRefGoogle ScholarPubMed
Wilson, H. (1964) Carotid body tumours: Surgical management. Annals of Surgery, 159: 959966.CrossRefGoogle ScholarPubMed
Wilson, H. (1966) Carotid body tumours. Surgery, 59: 483493.Google Scholar
Wilson, H. (1970) Carotid body tumours: Familial and bilateral. Annals of Surgery, 171: 843848.CrossRefGoogle ScholarPubMed
Wilson, M. A. (1979) Multiple chemodectomas. Journal of Nuclear Medicine, 20: 905906.Google ScholarPubMed
Zbaren, P., Lehmann, W. (1985) Carotid body paraganglioma with metastases. Laryngoscope, 95: 450453.CrossRefGoogle ScholarPubMed
Zeman, M. S. Carotid body tumours of the trachea (1956) Annals of Otology, Rhinology and Laryngology, 65: 960962CrossRefGoogle Scholar