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Minor salivary gland carcinomas of oral cavity and oropharynx

Published online by Cambridge University Press:  22 May 2009

H Chijiwa ,
K Sakamoto ,
H Umeno ,
T Nakashima ,
G Suzuki  and
N Hayafuchi
H Chijiwa*
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, Kurume, Japan
K Sakamoto
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, Kurume, Japan
H Umeno
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, Kurume, Japan
T Nakashima
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, Kurume, Japan
G Suzuki
Affiliation:
Department of Radiology, Kurume University School of Medicine, Kurume, Japan
N Hayafuchi
Affiliation:
Department of Radiology, Kurume University School of Medicine, Kurume, Japan
*
Address for correspondence: Dr Hideki Chijiwa, Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan. Fax: +81 942 37 1200 E-mail: [email protected]
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Abstract

This paper reviews 22 cases of minor salivary gland carcinoma of the oral cavity or oropharynx which were treated at Kurume University Hospital between 1976 and 2005. Minor salivary gland carcinoma was observed in eight of 362 patients with cancer of the oral cavity (2 per cent), and in 14 of 275 patients with cancer of the oropharynx (5 per cent). The five-year and 10-year survival rates of patients with oropharyngeal minor salivary gland carcinoma were 90 per cent. No statistically significant difference was observed between survival rates for oropharyngeal minor salivary gland carcinoma and for oropharyngeal squamous cell carcinoma (p = 0.06). The five- and 10-year survival rates of patients with oral cavity minor salivary gland carcinoma were 75 and 37 per cent, respectively. No statistically significant difference was observed between survival rates for oral cavity minor salivary gland carcinoma and oral cavity squamous cell carcinoma.

Patients' survival results correlated well with the clinical stage of their lesions. A significant difference in survival was observed, comparing stage IV with stages I, II and III (p = 0.04). In contrast, no significant relationship was found between either survival and tumour type or survival and treatment. Adjuvant therapy is recommended for patients with grade III adenoid cystic carcinoma with perineural infiltration or intravascular infiltration.

Keywords

Minor Salivary Gland CarcinomaOral CavityTreatmentSurvival Results
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 123 , Supplement S31 , May 2009 , pp. 52 - 57
Copyright
Copyright © JLO (1984) Limited 2009

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References

1Endo, S, Kida, A, Furusaka, T, Yamada, Y, Iida, H, Sakai, F et al. A clinical analysis of 37 cases of minor salivary gland carcinoma. Nippon Jibiinkoka Gakkai Kaiho 1995;78:136–46Google Scholar
2Katori, H, Tsukuda, M, Ishitoya, J, Kawano, T, Takahashi, M, Endo, R et al. Clinical analysis of a minor salivary gland tumor. Jpn J Otol 2005;51:428–31Google Scholar
3Szanto, PA, Luna, MA, Tortoledo, ME, White, RA. Histologic grading of adenoid cystic carcinoma of the salivary glands. Cancer 1984;54:1062–93.0.CO;2-E>CrossRefGoogle ScholarPubMed
4Crocker, DJ, Cavalaris, CJ, Finch, R. Intraoral minor salivary gland tumors. Oral Surg 1970;29:60–8CrossRefGoogle ScholarPubMed
5Goldblatt, LI, Ellis, GL. Salivary gland tumors of the tongue. Cancer 1987;60:74–813.0.CO;2-B>CrossRefGoogle ScholarPubMed
6Saikawa, M, Nigauri, T, Nishikawa, K. Report of head and neck cancer registry of Japan clinical statistics of registered patients, 2001. Jpn J Head Neck Cancer 2005;31:16–36Google Scholar
7Andersen, LJ, Therkildsen, MH, Ockelmann, HH, Bentzen, JD, Schiodt, T, Hansen, HS et al. Malignant epithelial tumors in the minor salivary glands, the submandibular gland, and the sublingual gland. Cancer 1991;68:2431–73.0.CO;2-N>CrossRefGoogle ScholarPubMed
8Namazie, A, Alavi, S, Abemayor, E. Adenoid cystic carcinoma of the base of the tongue. Ann Otol Rhinol Laryngol 2001;110:248–53CrossRefGoogle ScholarPubMed
9Sur, RK, Donde, B, Levin, V, Pacella, J, Kotzen, J, Cooper, K et al. Adenoid cystic carcinoma of the salivary glands: a review of 10 years. Laryngoscope 1997;107:1276–80CrossRefGoogle ScholarPubMed
10Goepfert, H, Giraldo, AA, Byers, RM, Luna, MA. Salivary gland tumors of the base of the tongue. Arch Otolaryngol 1976;102:391–5CrossRefGoogle ScholarPubMed
11Olsen, KD, Devine, KD, Weiland, LH. Mucoepidermoid carcinoma of the oral cavity. Otolaryngol Head Neck Surg 1981;89:783–91CrossRefGoogle ScholarPubMed
12Heidelberger, KP, Batsakis, JG. Mucoepidermoid carcinoma of the tongue. J Laryngol Otol 1973;87:1239–42CrossRefGoogle ScholarPubMed
13Kessler, DJ, Mickel, RA, Calcaterra, TC. Malignant salivary gland tumors of the base of the tongue. Arch Otolaryngol 1985;111:664–6CrossRefGoogle ScholarPubMed
14Umeno, H, Miyajima, Y, Mori, K, Nakashima, T. Clinicopathological study of cases of adenoid cystic carcinoma in head and neck. Nippon Jibiinkoka Gakkai Kaiho 1997;100:1442–9CrossRefGoogle ScholarPubMed
15Matsuda, K, Teshima, T. Clinicopathological study on cases of adenoid cystic carcinoma in head and neck. Jap Society of Stomato-Pharyngology 1994;40:438–53Google Scholar
16Hisa, Y, Yasuda, N, Tadaki, N, Nishiyama, Y, Hukushima, T, Murakami, Y et al. Adenoid cystic carcinoma of head and neck – clinical review of 29 cases. Nippon Jibiinkoka Gakkai Kaiho 1992;95:346–51Google Scholar
17Tsukuda, M. Choice of an anticancer drug in adenocarcinomas. Otolaryngol Head Neck Surg (Tokyo) 1990;62:193–6Google Scholar