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Malignant parotid salivary gland peripheral nerve sheath tumour in a twelve-year-old girl

Published online by Cambridge University Press:  29 June 2007

Anna C. Athow  and
Nigel Kirkham
Anna C. Athow
Affiliation:
Departments of Paediatric Surgery, Royal Alexandra Hospital
Nigel Kirkham*
Affiliation:
Departments of Histopathology, Royal Sussex County Hospital, Brighton.
*
Dr N. Kirkham, Dept of Histopathology, Royal Sussex County Hospital, Brighton BN2 5BE, UK. Fax 0273 600182
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Abstract

A case of a malignant parotid salivary gland nerve sheath tumour is reported in a 12-year-old girl who developed a right parotid mass. Initial incisional biopsy showed a tumour with a mesenchymal spindle cell appearance. Immunohistochemical studies showed positive staining of tumour cells for vimentin and focally for S-100 protein. These features together with ultrastructural evidence of basal lamina material suggested that the tumour was of nerve sheath origin. After subtotal parotidectomy the tumour metastasised to cervical lymph node and lung. There was evidence of a partial response to chemotherapy. A detailed illustrated histopathological description of the tumour is given.

Keywords

Parotid glandNervous systemneoplasms
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 8 , August 1992 , pp. 748 - 750
Copyright
Copyright © JLO (1984) Limited 1992

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