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Long-term effects of allergen-specific subcutaneous immunotherapy for house dust mite induced allergic rhinitis

Published online by Cambridge University Press:  17 October 2017

E Sahin ,
D Dizdar ,
M E Dinc  and
A A Cirik
E Sahin
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Bayındır Hospital Icerenkoy, Istanbul, Turkey
D Dizdar*
Affiliation:
Department of Otorhinolaryngology, Medical Park Bahçelievler Hospital, Faculty of Medicine, Istanbul Kemerburgaz University, Istanbul, Turkey
M E Dinc
Affiliation:
Department of Otorhinolaryngology, Gaziosmanpasa Taksim Education and Research Hospital, Turkish Ministry of Health, Istanbul, Turkey
A A Cirik
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Umraniye Research and Training Hospital, Istanbul, Turkey
*
Address for correspondence: Dr Denizhan Dizdar, Department of Otorhinolaryngology, Medical Park Bahçelievler Hospital, Faculty of Medicine, Istanbul Kemerburgaz University, Istanbul, Turkey E-mail: [email protected]
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Abstract

Background:

Allergic rhinitis is strongly associated with the presence of house dust mites. This study investigated the long-term effects of allergen-specific immunotherapy. Allergen-specific immunotherapy was applied over three years. The study was based on a 10-year follow up of patients with allergic rhinitis.

Methods:

The study was conducted between 2001 and 2015. Skin prick test results and symptom scores were evaluated before (26 patients) and after 3 years (20 patients) of allergen-specific immunotherapy (using data from a previously published study), and 10 years after allergen-specific immunotherapy had ended (20 of 26 patients).

Results:

The symptom scores before allergen-specific immunotherapy were significantly higher than those obtained after 3 years of allergen-specific immunotherapy and 10 years after allergen-specific immunotherapy (p < 0.0175). There were no significant differences between the scores obtained at 3 years and 10 years after allergen-specific immunotherapy (p > 0.0175).

Conclusion:

Subcutaneous immunotherapy is an effective treatment for house dust mite induced allergic rhinitis.

Keywords

AllergyImmunotherapySubcutaneous Immunotherapy
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 131 , Issue 11 , November 2017 , pp. 997 - 1001
Copyright
Copyright © JLO (1984) Limited 2017 

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