Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-28T07:35:16.376Z Has data issue: false hasContentIssue false
  • English
  • Français

Lichen planus of the larynx

Published online by Cambridge University Press:  28 January 2011

C E Rennie ,
R C Dwivedi ,
A S Khan ,
N Agrawal  and
W Ziyada
C E Rennie*
Affiliation:
Department of Otolaryngology, St Mary's Hospital, London, UK
R C Dwivedi
Affiliation:
Head and Neck Unit, Royal Marsden Hospital, London, UK
A S Khan
Affiliation:
Head and Neck Unit, Royal Marsden Hospital, London, UK
N Agrawal
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
W Ziyada
Affiliation:
Department of Otolaryngology, East Surrey Hospital, Redhill, UK
*
Address for correspondence: Miss Catherine Rennie, Department of Otolaryngology, St Mary's Hospital, London W2 1NY, UK Fax:  + 44 (0)207 886 1847 E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

We report an extremely rare case of laryngeal lichen planus.

Method:

A case report and literature review of the aetiopathogenesis, clinical features and management of laryngeal lichen planus are presented.

Results:

A male patient presented with hoarseness and a history suggestive of squamous cell carcinoma of the larynx. However, characteristic histopathological findings demonstrated lichen planus. The patient responded very well to oral steroids, and at the time of writing had remained symptom-free for two years.

Conclusion:

This is the first English language report of laryngeal lichen planus. Lichen planus is a diagnosis of exclusion and responds well to steroids. However, patients should be followed up regularly as malignant change is known to occur.

Keywords

Lichen PlanusLarynxDiagnosisTherapeutics
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 4 , April 2011 , pp. 432 - 435
Copyright
Copyright © JLO (1984) Limited 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Mollaoglu, N. Oral lichen planus: a review. Br J Oral Maxillofac Surg 2000;38:370–7CrossRefGoogle ScholarPubMed
2Kunel'skaia, Via, Arievich, AM. Lesion of the laryngeal mucosa in lichen ruber planus [in Russian]. Vestn Otorinolaringol 1978;5:32–5Google Scholar
3Setterfield, JF, Black, MM, Challacombe, SJ. The management of oral lichen planus. Clin Exp Dermatol 2000;25:176–82CrossRefGoogle ScholarPubMed
4Kim, SG, Chae, CH, Cho, BO, Kim, HN, Kim, HJ, Kim, IS et al. Apoptosis of oral epithelial cells in oral lichen planus caused by upregulation of BMP-4. J Oral Pathol Med 2006;35:37–45CrossRefGoogle ScholarPubMed
5McCartan, BE, McCreary, CE. Oral lichenoid drug eruptions. Oral disease 1997;3:58–63CrossRefGoogle ScholarPubMed
6Koch, P, Bahmer, FA. Oral lesions and symptoms related to metals used in dental restorations: a clinical, allergological, and histologic study. J Am Acad Dermatol 1999;41:422–30CrossRefGoogle ScholarPubMed
7Scully, C, Beyli, M, Ferreiro, MC, Ficarra, G, Gill, Y, Griffiths, M et al. Update on oral lichen planus: etiopathogenesis and management. Crit Rev Oral Biol Med 1998;9:86–122CrossRefGoogle ScholarPubMed
8Korkij, W, Chuang, TY, Soltani, K. Liver abnormalities in patients with lichen planus. A retrospective case-control study. J Am Acad Dermatol 1984;11:609–15CrossRefGoogle ScholarPubMed
9Silverman, S, Bahl, S. Oral lichen planus: clinical characteristics, treatment responses, and malignant transformation. Am J Dent 1997;10:256–63Google ScholarPubMed
10Lo Muzio, L, Mignogna, MD, Favia, G, Procaccinic, M, Testaa, NF, Bucci, E. The possible association between oral lichen planus and oral squamous cell carcinoma: a clinical evaluation of 14 cases and review of literature. Oral Oncol 1998;34:239–46CrossRefGoogle Scholar
11Carbone, M, Conrotto, D, Carrozzo, M, Broccoletti, R, Gandolfo, S, Scully, C. Topical corticosteroids in association with miconazole and chlorhexidine in the long-term management of atrophic-erosive oral lichen planus: a placebo-controlled and comparative study between clobetasol and fluocinonide. Oral Dis 1999;5:44–9CrossRefGoogle ScholarPubMed
12Carbone, M, Goss, E, Carrozzo, M, Castellano, S, Conrotto, D, Broccoletti, R et al. Systemic and topical corticosteroid treatment of oral lichen planus: a comparative study with long-term follow-up. J Oral Pathol Med 2003;32:323–9CrossRefGoogle ScholarPubMed
13Scully, C, Carrozzo, M. Oral mucosal disease: lichen planus. Br J Oral Maxillofac Surg 2008;46:15–21CrossRefGoogle ScholarPubMed
14Lozada-Nur, F, Miranda, C. Oral lichen planus: topical and systemic therapy. Semin Cutan Med Surg 1997;16:295–300CrossRefGoogle ScholarPubMed
15Boyd, AS, Neldner, KH. Lichen planus. J Am Acad Dermatol 1991;25:593–619CrossRefGoogle ScholarPubMed
16Kaliakatsou, F, Hodgson, TA, Lewsey, JD, Hegarty, AM, Murphy, AG, Porter, SR. Management of recalcitrant ulcerative oral lichen planus with topical tacrolimus. J Am Acad Dermatol 2002;46:35–41CrossRefGoogle ScholarPubMed
17Camisa, C, Popovsky, JL. Effective treatment of oral erosive lichen planus with thalidomide. Arch Dermatol 2000;136:1442–3CrossRefGoogle ScholarPubMed