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Lemierre's syndrome – an unusual complication of otitis externa in a young, healthy female

Published online by Cambridge University Press:  08 October 2014

N Davidoss ,
J F Ha ,
J R Anderson  and
S Rodrigues
N Davidoss*
Affiliation:
Department of Ear, Nose and Throat, Royal Perth Hospital, Western Australia, Australia
J F Ha
Affiliation:
Department of Ear, Nose and Throat, Royal Perth Hospital, Western Australia, Australia
J R Anderson
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Fremantle Hospital, Western Australia, Australia
S Rodrigues
Affiliation:
Department of Ear, Nose and Throat, Royal Perth Hospital, Western Australia, Australia
*
Address for correspondence: Dr Nishant Davidoss, Department of Ear, Nose and Throat, Royal Perth Hospital, Wellington Street Campus, 197 Wellington Street, Perth, WA 6000, Australia E-mail: [email protected]
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Abstract

Background:

Lemierre's syndrome, which affects previously healthy, young adults, is a rare complication secondary to infections in the head and neck that result in septic thrombophlebitis of the internal jugular vein.

Method:

This paper reports a case of a young, healthy female with malignant otitis externa, which resulted in the development of Lemierre's syndrome. A review of the relevant literature was also carried out. This involved a search of the Medline database using multiple search terms including ‘Lemierre’, ‘septic thrombophlebitis’, ‘otitis externa’, ‘internal jugular vein thrombosis’ and ‘management’.

Results:

The patient presented with fever, left-sided otalgia, otorrhoea, neck swelling and pain. She was subsequently diagnosed with Lemierre's syndrome and managed accordingly.

Conclusion:

Lemierre's syndrome is a potentially fatal complication associated with significant morbidity. A high index of suspicion is required for prompt recognition and the early institution of treatment.

Keywords

Lemierre SyndromeThrombophlebitisOtitis ExternaJugular VeinThrombosisReviewDisease Management
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 129 , Issue S1 , January 2015 , pp. S60 - S62
Copyright
Copyright © JLO (1984) Limited 2014 

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Footnotes

Presented orally at the Australian Society of Otolaryngology Head and Neck Surgery (ASOHNS) 2013 Annual Scientific Meeting, 16–20 March 2013, Perth, Western Australia, Australia.

References

1Lemierre, A. On certain septicemias due to anaerobic organisms. Lancet 1936;227:701–3CrossRefGoogle Scholar
2Karkos, P, Asrani, S, Karkos, C, Leong, S, Theochari, E, Alexopoulou, T et al. Lemierre's syndrome: a systematic review. Laryngoscope 2009;119:1552–9CrossRefGoogle ScholarPubMed
3Riordan, T. Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre's syndrome. Clin Microbiol Rev 2007;20:622–59CrossRefGoogle ScholarPubMed
4Kuppalli, K, Livorsi, D, Talati, N, Osborn, M. Lemierre's syndrome due to Fusobacterium necrophorum. Lancet Infect Dis 2012;12:808–15Google Scholar
5Hile, LM, Gibbons, MD, Hile, DC. Lemierre syndrome complicating otitis externa: case report and literature review. J Emerg Med 2012;42:e77–e80CrossRefGoogle ScholarPubMed
6Auber, AE, Mancuso, PA. Lemierre syndrome: magnetic resonance imaging and computed tomographic appearance. Mil Med 2000;165:638–40CrossRefGoogle ScholarPubMed
7Aliyu, SH, Marriott, RK, Curran, MD, Parmar, S, Bentley, N, Brown, NM et al. Real-time PCR investigation into the importance of Fusobacterium necrophorum as a cause of acute pharyngitis in general practice. J Med Microbiol 2004;53:1029–35CrossRefGoogle ScholarPubMed
8Charles, K, Flinn, W, Neschis, D. Lemierre's syndrome: a potentially fatal complication that may require vascular surgical intervention. J Vasc Surg 2005;42:1023–5CrossRefGoogle ScholarPubMed
9Golpe, R, Marín, B, Alonso, M. Lemierre's syndrome (necrobacillosis). Postgrad Med J 1999;75:141–4Google Scholar
10Armstrong, AW, Spooner, K, Sanders, JW. Lemierre's syndrome. Curr Infect Dis Rep 2000;2:168–73CrossRefGoogle ScholarPubMed
11Bondy, P, Grant, T. Lemierre's syndrome: what are the roles for anticoagulation and long-term antibiotic therapy? Ann Otol Rhinol Laryngol 2008;117:679–83CrossRefGoogle ScholarPubMed
12Venglarcik, J. Lemierre's syndrome. Pediatr Infect Dis J 2003;22:921–3Google Scholar
13Hagelskjaer Kristensen, L, Prag, J. Human necrobacillosis, with emphasis on Lemierre's syndrome. Clin Infect Dis 2000;31:524–32Google Scholar