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Intratympanic steroid injection as a salvage treatment for sudden sensorineural hearing loss

Published online by Cambridge University Press:  17 November 2014

S Belhassen  and
I Saliba
S Belhassen
Affiliation:
Division of Otolaryngology—Head and Neck Surgery, University of Montreal, Quebec, Canada
I Saliba*
Affiliation:
Montreal University Hospital Centre (CHUM), Quebec, Canada
*
Address for correspondence: Prof I Saliba, Otolaryngology Department, Centre Hospitalier de l'Université de Montréal – Notre-Dame Hospital, 1560 Sherbrooke East Montreal, Quebec, Canada H2L 4 M1 Fax: +1 514 737–4822 E-mail: [email protected]
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Abstract

Objective:

To determine the efficacy of intratympanic methylprednisolone injections for treating sudden sensorineural hearing loss.

Method:

A retrospective chart review was performed to identify patients suffering from sudden sensorineural hearing loss with no recovery after oral steroids. Patients were given up to three intratympanic methylprednisolone injections at one-week intervals. They were classified according to their functional hearing class, remission was monitored and potential factors affecting prognosis were analysed.

Results:

Intratympanic injections provide effective salvage therapy for sudden sensorineural hearing loss (p = 0.039). Changes in pure tone average and speech discrimination score were analysed following intratympanic methylprednisolone injections. The pure tone average reached a plateau after the second injection; however, the speech discrimination score improved until after the third injection. Hearing improvement after intratympanic injections mainly occurred at low frequencies. The interval between symptoms appearing and intratympanic injections starting was not significantly associated with remission (p = 0.680).

Conclusion:

A delay between symptom onset and the first intratympanic methylprednisolone injection does not seem to affect prognosis.

Keywords

Hearing Loss, SuddenSteroidsSalvage TherapyMethylprednisolone
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 128 , Issue 12 , December 2014 , pp. 1044 - 1049
Copyright
Copyright © JLO (1984) Limited 2014 

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