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Hypopharyngeal presentation of cicatricial pemphigoid: videofluorographic and direct laryngoscopic findings

Published online by Cambridge University Press:  26 February 2013

S Murono ,
Y Nakanishi ,
M Fujimoto  and
T Yoshizaki
S Murono*
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, School of Medicine, Kanazawa University, Japan
Y Nakanishi
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, School of Medicine, Kanazawa University, Japan
M Fujimoto
Affiliation:
Department of Dermatology, School of Medicine, Kanazawa University, Japan
T Yoshizaki
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, School of Medicine, Kanazawa University, Japan
*
Address for correspondence: Dr S Murono, Department of Otolaryngology, Head and Neck Surgery, School of Medicine, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8640, Japan Fax: 81-76-234-4265 E-mail: [email protected]
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Abstract

Objective:

Cicatricial pemphigoid can affect all mucosa of the upper aerodigestive tract; however, hypopharyngeal involvement is less frequent.

Case report:

This paper presents a 69-year-old male diagnosed as having cicatricial pemphigoid who was experiencing difficulty swallowing. Videofluorography with barium swallow demonstrated narrow flow through the medial hypopharynx, but not through the lateral hypopharynx. Direct laryngoscopy revealed that the postcricoid hypopharyngeal lumen had become narrow due to circumferential scar formation. Interestingly, detached thin membranous webs were observed beyond the circumferential scar.

Conclusion:

This report describes important videofluorographic and direct laryngoscopic findings showing rare hypopharyngeal involvement in a case of cicatricial pemphigoid.

Keywords

Cicatricial pemphigoidVideofluorographyHypopharynxLaryngoscopyStenosis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 4 , April 2013 , pp. 429 - 431
Copyright
Copyright © JLO (1984) Limited 2013

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References

1Hanson, RD, Olsen, KD, Rogers, RS 3rd. Upper aerodigestive tract manifestations of cicatricial pemphigoid. Ann Otol Rhinol Laryngol 1988;97:493–9CrossRefGoogle ScholarPubMed
2Alexandre, M, Brette, MD, Pascal, F, Tsianakas, P, Fraitag, S, Doan, S et al. A prospective study of upper aerodigestive tract manifestations of mucous membrane pemphigoid. Medicine (Baltimore) 2006;85:239–52CrossRefGoogle ScholarPubMed
3Bruch-Gerharz, D, Hertl, M, Ruzicka, T. Mucous membrane pemphigoid: clinical aspects, immunopathological features and therapy. Eur J Dermatol 2007;17:191–200Google ScholarPubMed
4Anhalt, GJ, Morrison, LH.Bullous and cicatricial pemphigoid. J Autoimmun 1991;4:17–35CrossRefGoogle ScholarPubMed
5Ahmed, AR, Hombal, SM. Cicatricial pemphigoid. Int J Dermatol 1986;25:90–6CrossRefGoogle ScholarPubMed
6Syn, WK, Ahmed, MM.Esophageal involvement in cicatricial pemphigoid: a rare cause of dysphagia. Dis Esophagus 2004;17:180–2CrossRefGoogle ScholarPubMed
7Naylor, MF, MacCarty, RL, Rogers, RS 3rd. Barium studies in esophageal cicatricial pemphigoid. Abdom Imaging 1995;20:97–100CrossRefGoogle ScholarPubMed
8Soong, C, Bynum, TE. The endoscopic appearance of pemphigoid esophagitis. Gastrointest Endos 1972;19:17–18CrossRefGoogle ScholarPubMed
9Watkinson, AF, Vretenar, DF, Morrison, MD, Burhenne, HJ.Benign mucous membrane pemphigoid: treatment of esophageal stricture. Can Assoc Radiol J 1994;45:140–2Google ScholarPubMed
10Sullivan, CA, Jaklitsch, MT, Haddad, R, Goguen, LA, Gagne, A, Wirth, LJ et al. Endoscopic management of hypopharyngeal stenosis after organ sparing therapy for head and neck cancer. Laryngoscope 2004;114:1924–31CrossRefGoogle ScholarPubMed