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Excision and low-dose radiotherapy for refractory laryngeal granuloma

Published online by Cambridge University Press:  29 June 2007

G. Mitchell*
Affiliation:
Head and Neck Unit, Royal Marsden Hospital NHS Trust, London, UK
C. R. Pearson
Affiliation:
Head and Neck Unit, Royal Marsden Hospital NHS Trust, London, UK
J. M. Henk
Affiliation:
Head and Neck Unit, Royal Marsden Hospital NHS Trust, London, UK
P. Rhys-Evans
Affiliation:
Head and Neck Unit, Royal Marsden Hospital NHS Trust, London, UK
*
Address for correspondence: Dr G. Mitchell, Head and Neck Unit, Royal Marsden NHS Trust, Fulham Road, London

Abstract

Laryngeal granulomas are uncommon lesions of an inflammatory origin. They are conventionally managed by simple excision with the occasional use of adjuvant treatment depending on the aetiological factors. Unfortunately, recurrences can occur, requiring repeated excision. Some lesions are refractory to this approach and alternative management approaches include excision and immediate adjuvant radiotherapy. The use of radiotherapy in the management of benign disease can be limited by the risk of induction of late malignancy and informed consent of a patient must include an assessment of this risk. We describe a case of refractory laryngeal granuloma successfully treated by excision and immediate radiotherapy in a patient occupationally dependent upon his voice.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1998

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References

Balestrieri, F., Watson, C. B. (1982) Intubation granuloma. Otolarvngologic Clinics of North America 15: 567579.CrossRefGoogle ScholarPubMed
Benjamin, B., Croxson, G. (1985) Vocal cord granulomas. Annals of Otology, Rhinology and Laryngology 94: 538541.CrossRefGoogle ScholarPubMed
Davy, A. O. (1959) Laryngeal granuloma, with special reference to cases in Australia. Medical Journal of Australia 1: 617620.CrossRefGoogle Scholar
Hall, E. J. (1994) Radiobiology for the Radiologist. J. B. Lippincott Company, Philadelphia, pp 324350.Google Scholar
Harari, P. M., Blatchford, S. J., Coulthard, S. W., Cassady, J. R. (1991) Intubation granuloma of the larynx: Successful eradication with low-dose radiotherapy. Head and Neck 13: 230233.CrossRefGoogle ScholarPubMed
Jaroma, M., Pakarinen, L., Nuutinen, J. (1989) Treatment of vocal cord granuloma. Acta Otolaryngologica (Stockh) 107: 296299.CrossRefGoogle ScholarPubMed
Keiser, G. J., Bozentka, N. E., Gold, B. D. (1991) Laryngeal granuloma: A complication of prolonged endotracheal intubation. Anesthesia Progress 38: 232234.Google ScholarPubMed
McFerran, D. J., Abdullah, V., Gallimore, A. P., Pringle, M. B., Croft, C. B. (1994) Vocal process granulomata. Journal of Laryngology and Otology 108: 216220.CrossRefGoogle ScholarPubMed
Nasri, S., Sercarz, J. A., McAlpin, T., Berke, G. S. (1995) Treatment of vocal cord granuloma using botulinum toxin type A. Laryngoscope 105: 585588.CrossRefGoogle ScholarPubMed
Serber, W., Amendola, B. E. (1992) Radiation treatment of benign disease. In Principles and Practice of Radiation Oncology. 2nd Edition, (Perez, C. A. and Brady, L. W., eds.), J. B. Lippincott Company, Philadelphia, pp 14761485.Google Scholar
Shapshay, S. M., Rebeiz, E. E., Bohigian, R. K., Hybels, R. L. (1990) Benign lesions of the larynx: should the laser be used? Laryngoscope 100(9): 953957.CrossRefGoogle ScholarPubMed
Smith, R. O., Hemenway, W. G., English, G. M., Black, F. O., Swan, H. (1969) Post-intubation subglottic granulation tissue: review of the problem and evaluation of radiotherapy. Laryngoscope 79: 12271251.CrossRefGoogle ScholarPubMed
Tonkin, J. P., Harrison, G. A. (1971) The surgical management of the laryngeal complications of prolonged intubation. Laryngoscope 81: 297307.CrossRefGoogle ScholarPubMed
van Leeuwen, F. E., Klokman, W. J., Hagenbeek, A., Noyan, A. W., van den Belt-Dusebout, A. W., van Kerkhoff, E. H. M., van Heerde, P., Somers, R. (1994) Second cancer risk following Hodgkin's Disease: A 20 year follow up study. Journal of Clinical Oncology 12: 312325.CrossRefGoogle ScholarPubMed
Wenig, B. M., Heffner, D. K. (1990) Contact ulcers of the larynx. Archives of Pathology and Laboratory Medicine 114: 825828.Google ScholarPubMed