Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-27T18:30:08.727Z Has data issue: false hasContentIssue false
  • English
  • Français

The evaluation of nasal mucociliary clearance in patients with Helicobacter pylori infection

Published online by Cambridge University Press:  06 February 2019

S Üstün Bezgin ,
T Çakabay ,
K Irak ,
M Koçyiğit ,
B Serin Keskineğe  and
S Giran Örtekin
S Üstün Bezgin*
Affiliation:
Department of Otorhinolaryngology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
T Çakabay
Affiliation:
Department of Otorhinolaryngology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
K Irak
Affiliation:
Department of Gastroenterology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
M Koçyiğit
Affiliation:
Department of Otorhinolaryngology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
B Serin Keskineğe
Affiliation:
Department of Otorhinolaryngology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
S Giran Örtekin
Affiliation:
Department of Otorhinolaryngology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey
*
Author for correspondence: Dr Selin Üstün Bezgin, Otorhinolaryngology Department, Kanuni Sultan Süleyman Education and Research Hospital, Atakent mahallesi, Turgut Özal caddesi No: 1, 34303, Altınşehir, Küçükçekmece, Istanbul, Turkey E-mail: [email protected] Fax: +90 212 5714790
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective

This study aimed to examine nasal mucociliary clearance time in patients with Helicobacter pylori infection.

Methods

Fifty patients who were newly diagnosed with H pylori infection using gastric biopsy in the gastroenterology out-patient clinic, and 50 age- and gender-matched healthy adults who were admitted to the otorhinolaryngology out-patient clinic, were included in this study. After an otorhinolaryngological examination (anterior rhinoscopy and nasal endoscopic examination), the nasal mucociliary clearance time of each subject was calculated using the saccharine test.

Results

The mean mucociliary clearance time was 06:29 ± 3:31 minutes (range, 00:55–15:19 minutes) in the control group and 10:12 ± 06:09 minutes (range, 01:28–32:00 minutes) in the study group. Comparisons of the two groups revealed a statistically significant difference (p = 0.002).

Conclusion

Nasal mucociliary clearance time was significantly increased in patients with H pylori infection. The results suggest that H pylori infection may have an unfavourable effect on nasal mucociliary clearance.

Keywords

Mucociliary ClearanceHelicobacter PyloriSaccharine
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 133 , Issue 3 , March 2019 , pp. 220 - 223
Copyright
Copyright © JLO (1984) Limited, 2019 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Dr S Ü Bezgin takes responsibility for the integrity of the content of the paper

References

1Suerbaum, S, Michetti, P. Helicobacter pylori infection. N Engl J Med 2002;347:1175–86Google Scholar
2Song, Q, Lange, T, Spahr, A, Adler, G, Bode, G. Characteristic distribution pattern of Helicobacter pylori in dental plaque and saliva detected with nested PCR. J Med Microbiol 2000;49:349–53Google Scholar
3Bayındır, T, Toplu, Y, Otlu, B, Yakupogulları, Y, Yıldırım, O, Kalcıoglu, MT. Prevalence of the Helicobacter pylori in the tonsils and adenoids. Braz J Otorhinolaryngol 2015;81:307–11Google Scholar
4Saki, N, Nikakhlagh, S, Ahmadi, K. Comparison of PCR assay and culture for detecting bacteria in middle ear fluid of children with otitis media with effusion. J Int Adv Otol 2009;5:31–4Google Scholar
5Ozdek, A, Cirak, MY, Samim, E, Bayiz, U, Safak, MA, Turet, S. A possible role of Helicobacter pylori in chronic rhinosinusitis: a preliminary report. Laryngoscope 2003;113:679–82Google Scholar
6Koç, C, Arikan, OK, Atasoy, P, Aksoy, A. Prevalence of Helicobacter pylori in patients with nasal polyps: a preliminary report. Laryngoscope 2004;114:1941–4Google Scholar
7Morinaka, S, Ichimiya, M, Nakamura, H. Detection of Helicobacter pylori in nasal and maxillary sinus specimens from patients with chronic sinusitis. Laryngoscope 2003;113:1557–63Google Scholar
8Kim, HY, Dhong, HJ, Chung, SK, Chung, KW, Chung, YJ, Jang, KT. Intranasal Helicobacter pylori colonization does not correlate with the severity of chronic rhinosinusitis. J Otolaryngol Head Neck Surg 2007;136:390–5Google Scholar
9Dinis, PB, Subtil, J. Helicobacter pylori and laryngopharyngeal reflux in chronic rhinosinusitis. J Otolaryngol Head Neck Surg 2006;134:67–72Google Scholar
10Stevens, WW, Lee, RJ, Schleimer, RP, Cohen, NA. Chronic rhinosinusitis pathogenesis. J Allergy Clin Immunol 2015;136:1442–53Google Scholar
11Andersen, I, Camner, P, Jensen, PL, Philipson, K, Proctor, DF. A comparison of nasal and tracheobronchial clearance. Arch Environ Health 1974;29:290–3Google Scholar
12Rutland, J, Cole, PJ. Nasal mucociliary clearance and ciliary beat frequency in cystic fibrosis compared with sinusitis and bronchiectasis. Thorax 1981;36:654–8Google Scholar
13Gudis, DA, Cohen, NA. Cilia dysfunction. Otolaryngol Clin North Am 2010;43:461–72Google Scholar
14Gudis, D, Zhao, KQ, Cohen, NA. Acquired cilia dysfunction in chronic rhinosinusitis. Am J Rhinol Allergy 2012;26:1–6Google Scholar
15Taylor, DN, Blaser, MJ. The epidemiology of Helicobacter pylori infection. Epidemiol Rev 1991;13:42–59Google Scholar
16Deborah, S, Prathibha, KM. Measurement of nasal mucociliary clearance. Clin Res Pulmonol 2014;2:1019Google Scholar
17Pandya, VK, Tiwari, RS. Nasal mucociliary clearance in health and disease. Indian J Otolaryngol Head Neck Surg 2006;58:332–4Google Scholar
18El-Sarag, HB, Sonnenberg, A. Comorbid occurrence of laryngeal or pulmonary disease with esophagitis in United States military veterans. Gastroenterology 1007;113:755–60Google Scholar
19Ulualp, SO, Toohill, RJ, Hoffmann, R, Shaker, R. Possible relationship of gastroesophagopharyngeal acid reflux with pathogenesis of chronic sinusitis. Am J Rhinol 1999;13:197–202Google Scholar
20Delehaye, E, Dore, MP, Bozzo, C, Mameli, L, Delitala, G, Meloni, F. Correlation between nasal mucociliary clearance time and gastroesophageal reflux disease: our experience on 50 patients. Auris Nasus Larynx 2009;36:157–61Google Scholar