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Epithelioid haemangioendothelioma arising in the nasal cavity

Published online by Cambridge University Press:  08 March 2006

Alberto Di Girolamo ,
Pier Giorgio Giacomini ,
Antonella Coli ,
Federica Castri ,
Alessandro de Padova  and
Giulio Bigotti
Alberto Di Girolamo
Affiliation:
Department of Otolaryngology, ’Tor Vergata’ University, Rome, Italy.
Pier Giorgio Giacomini
Affiliation:
Department of Otolaryngology, ’Tor Vergata’ University, Rome, Italy.
Antonella Coli
Affiliation:
Department of Anatomic Pathology, Catholic University of Sacred Heart, Rome, Italy.
Federica Castri
Affiliation:
Department of Anatomic Pathology, Catholic University of Sacred Heart, Rome, Italy.
Alessandro de Padova
Affiliation:
Department of Otolaryngology, ’Tor Vergata’ University, Rome, Italy.
Giulio Bigotti
Affiliation:
Department of Anatomic Pathology, Catholic University of Sacred Heart, Rome, Italy.
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Abstract

We report here the case of an epithelioid haemangioendothelioma (EHE) arising in the nasal cavity which is, to the best of our knowledge, the first ever described example in the world literature in that particular site.

The patient is a 23-year-old male who presented with repeated episodes of epistaxis from the nasal cavity and with a 1.5 cm reddish, polypoid, smooth, spontaneously bleeding nodule in the rightmiddle meatus. This lesion was histologically diagnosed as epithelioid haemangioendothelioma. Immunohistochemically the neoplasm displayed striking positivity for CD31, CD34 and vimentin. A surgical approach was performed by ’facial degloving’, removing the right inferior turbinate, the anterior two-thirds of the middle turbinate and the medial wall of the ethmoid bone. After 12 months follow-up the patient is disease-free, without any local or distant recurrence.

Keywords

HaemangioendotheliomaEpitheloidNasal Cavity
Type
Other
Information
The Journal of Laryngology & Otology , Volume 117 , Issue 1 , January 2003 , pp. 75 - 77
Copyright
© Royal Society of Medicine Press Limited 2003

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