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Epithelial-myoepithelial carcinoma – Report of a case arising in the nasal cavity

Published online by Cambridge University Press:  29 June 2007

Hiroshi Harada ,
Sho-Ichi Kashiwagi ,
Hitomi Fujiura ,
Jingo Kusukawa  and
Minoru Morimatsu
Hiroshi Harada*
Affiliation:
Second Department of Pathology, Kurume University School of Medicine, Kurume, Japan
Sho-Ichi Kashiwagi
Affiliation:
Second Department of Pathology, Kurume University School of Medicine, Kurume, Japan
Hitomi Fujiura
Affiliation:
Department of Otolaryngology, Kurume University School of Medicine, Kurume, Japan
Jingo Kusukawa
Affiliation:
Department of Oral and Maxillofacial Surgery, Kurume University School of Medicine, Kurume, Japan
Minoru Morimatsu
Affiliation:
Second Department of Pathology, Kurume University School of Medicine, Kurume, Japan
*
Address for correspondence: Dr Hiroshi Harada, The Second Department of Pathology, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830, Japan. Fax: 81 942 31-0342
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Abstract

We present an extremely rare case of epithelial-myoepithelial carcinoma (EMC) arising in the nasal cavity. The patient was a 56-year-old Japanese male with a polypoid tumour arising from the nasal septum. Histopathological examination revealed the tumour to consist of a solid proliferation of clear-cells and, in some areas, small or elongated duct structures with a double-layered arrangement of inner cuboidal cells and outer clear-cells. Dual differentiation toward myoepithelial and ductal cells were confirmed immunohistochemically. The occurrence of EMC in the nasal cavity is possible and this entity should be generally recognized by surgical pathologists, not only those engaged in head and neck surgery.

Keywords

Nasal septumCarcinomaMyoepithelial tumourAbstract.
Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 4 , April 1996 , pp. 397 - 400
Copyright
Copyright © JLO (1984) Limited 1996

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References

Chen, K. T. K. (1983) Clear cell carcinoma of the salivary gland. Human Pathology 14: 91–93.CrossRefGoogle ScholarPubMed
Collina, G., Gale, N., Visona, A., Betts, C. M., Cenacchi, V., Eusebi, V. (1991) Epithelial-myoepithelial carcinoma of the parotid gland: a clinico-pathologic and immunohistochemical study of seven cases. Tumori 77: 257–263.CrossRefGoogle ScholarPubMed
Corio, R. L., Sciubba, J. J., Brannon, R. B., Batsakis, J. G. (1982) Epithelial-myoepithelial carcinoma of intercalated duct origin. Oral Surgery 53: 280–287.CrossRefGoogle ScholarPubMed
Daley, T. D., Wysoki, G. P., Smout, M. S., Slinger, R. P. (1984) Epithelial-myoepithelial carcinoma of salivary glands. Oral Surgery 57: 512–519.CrossRefGoogle ScholarPubMed
Donath, K., Seifert, G., Schmitz, R. (1972) Zur Diagnose und Ultrastruktur des tubularen Speichelgangcarcinoms: Epithelial-myoepitheliales Schalstrukcacinom. Virchows Archiv für pathologische Anatomie und Physiologie and für klinische Medizin 356: 16–31.Google Scholar
Fonseca, I., Soares, J. (1993) Epithelial-myoepithelial carcinoma of the salivary gland. A study of 22 cases. Virchows Archiv für pathologische Anatomie 422: 389–396.CrossRefGoogle Scholar
Goldman, R. L., Klein, H. Z. (1972) Glycogen-rich adenoma of the parotid gland. An uncommon benign clear-cell tumor resembling certain clear cell carcinomas of salivary origin. Cancer 30: 749–754.3.0.CO;2-9>CrossRefGoogle ScholarPubMed
Hamper, K., Brugmann, M., Koppermann, R., Caselitz, J., Arps, H., Askensten, U., Auer, G., Seifert, G. (1989) Epithelial-myoepithelial carcinoma of salivary glands: a follow-up and cytophotometric study of 21 cases. Journal of Oral Pathology and Medicine 18: 299–304.CrossRefGoogle ScholarPubMed
Horinouchi, H., Ishihara, T., Kawamura, M., Kato, R., Kikuchi, K., Kobayashi, K., Maenaka, Y., Torikata, C. (1993) Epithelial myoepithelial tumour of the tracheal gland. Journal of Clinical Pathology 46: 185–187.CrossRefGoogle ScholarPubMed
Littman, C. D., Alguacil-Garcic, A. (1987) Clear cell carcinoma arising in pleomorphic adenoma of the salivary gland. American Journal of Clinical Pathology 88: 239–243.CrossRefGoogle ScholarPubMed
Luna, M. A., Ordonez, N. G., Mackay, B., Mackay, B., Batsakis, J. G., Guillamondegui, O. (1985) Salivary epithelial-myoepithelial carcinomas of intercalated ducts: A clinical, electron microscopic, and immunohistochemical study. Oral Surgery 59: 482–490.CrossRefGoogle Scholar
Makek, M., Grant, J. W. (1988) Epithelial-myoepithelial carcinoma of the parotid gland associated with a primary carcinoma of the lung. International Journal of Oral Maxillofacial Surgery 17: 134–137.CrossRefGoogle ScholarPubMed
Mikaelian, D. O., Contrucci, R. B., Batsakis, J. G. (1986) Epithelial-myoepithelial carcinoma of the subglottic region: A case presentation and review of the literature. Otolaryngology-Head and Neck Surgery 95: 104–106.CrossRefGoogle ScholarPubMed
Mohamed, A. H., Cherrick, H. M. (1975) Glycogen-rich adenocarcinoma of minor salivary glands. A light and electron microscopic study. Cancer 36: 1057–1066.3.0.CO;2-P>CrossRefGoogle ScholarPubMed
Morinaga, S., Hashimoto, S., Tezuka, F. (1992) Epithelialmyoepithelial carcinoma of the parotid gland in a child. Acta Pathologica Japan 42: 358–363.CrossRefGoogle ScholarPubMed
Nistal, M., Garcia-Viera, M., Martinez-Garcia, C., Paniagua, R. (1994) Epithelial-myoepithelial tumor of the bronchus. American Journal of Surgical Pathology 18: 421–425.CrossRefGoogle ScholarPubMed
Noel, S., Bronza, J. P. (1992) Epithelial-myoepithelial carcinoma of salivary gland with metastasis to lung: report of a case and review of the literature. Head and Neck 14: 401–406.CrossRefGoogle ScholarPubMed
Ostrowski, M. L., Font, R. L., Halpern, J., Nicolitz, E., Barnes, R. (1994) Clear cell epithelial-myoepithelial carcinoma arising in pleomorphic adenoma of the lacrimal gland. Ophthalmology 101: 925–930.CrossRefGoogle ScholarPubMed
Palmer, R. M. (1985) Epithelial-myoepithelial carcinoma: an immunohistochemical study. Oral Surgery 59: 511–515.CrossRefGoogle Scholar
Porgel, M. A. (1985) Follow-up report on epithelial-myoepithelial carcinoma of intercalated duct origin. Oral Surgery 59: 172–173.Google Scholar
Saksela, E., Tarkkanen, J., Wartvaara, J. (1972) Parotid clearcell adenoma of possible myoepithelial origin. Cancer 30: 742–748.3.0.CO;2-X>CrossRefGoogle ScholarPubMed
Seifert, G., Sobin, L. H., Batsakis, J. G., Brocheriou, C., Cardesa, A., Dardick, I., Ellis, G. L., Eveson, J. W., Gusterson, B. A., Shanmugaratnam, K. (1991) Histologkal Typing of Salivary Gland Tumours. 2nd Edition, Springer-Verlag, Berlin, pp 23–24.CrossRefGoogle Scholar
Shanmugaratnam, K., Sobin, L. H., Barnes, L., Cardesa, A., Ferlito, A., Friedmann, I., Heffner, D. K., Hellquist, H. B., Hyams, V. J., Krueger, G. R. F., Micheau, C., Nascimento, A. (1991) Histologkal Typing of Tumours of the Upper Respiratory Tract and Ear. 2nd Edition, Springer-Verlag, Berlin, pp 37–38.CrossRefGoogle Scholar
Simpson, R. H. W., Clarke, T. J., Sarsfield, P. T. L., Gluckman, P. G. C. (1991) Epithelial-myoepithelial carcinoma of salivary glands. Journal of Clinical Pathology 44: 419–423.CrossRefGoogle ScholarPubMed
Thackray, A. C., Sobin, L. H. (1972) Histologkal Typing of Salivary Gland Tumours. World Health Organization, Geneva, p 16.Google Scholar
Witterick, I. J., Noyek, A. M., Chapnik, J. S., Heatoce, J. G., Bedard, Y. C. (1993) Observation on the natural history of a parotid epithelial-myoepithelial carcinoma of intercalated duct. Journal of Otolaryngology 22: 176–179.Google Scholar