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Tricarboxylic acid cycle enzymes of a pseudophyllid cestode Penetrocephalus ganapatii

Published online by Cambridge University Press:  05 June 2009

S. Dhandayuthapani  and
K. Nellaiappan
S. Dhandayuthapani
Affiliation:
Department of Zoology, University of Madras, Guindy Campus, Madras – 600 025, India.
K. Nellaiappan
Affiliation:
Department of Zoology, University of Madras, Guindy Campus, Madras – 600 025, India.
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Abstract

Studies on the tricarboxylic acid cycle (TCA cycle) enzymes of Penetrocephalus ganapatii reveal that the TCA cycle is only partially operative, as some of the enzymes at the start of the cycle viz. citrate synthase, aconitase and isocitrate dehydrogenase are found to be low in their activities. The high activities of malate dehydrogenase and fumarase, showing affinity towards a reverse direction, indicate that the TCA cycle operates in the reverse direction resulting in the formation of fumarate. The low succinate dehydrogenase/fumarate reductase ratio suggests that ATP generation may occur at site I of the respiratory chain during the reduction of fumarate into succinate.

Keywords

Penetrocephalus ganapatiitricarboxylic acid cycleenzymes
Type
Research Note
Information
Journal of Helminthology , Volume 64 , Issue 1 , March 1990 , pp. 51 - 53
Copyright
Copyright © Cambridge University Press 1990

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