Hostname: page-component-78c5997874-v9fdk Total loading time: 0 Render date: 2024-11-08T00:15:23.335Z Has data issue: false hasContentIssue false
  • English
  • Français

Studies with Brugia pahangi. 16. Precipitation antibody in infected cats detected by counterimmunoelectrophoresis

Published online by Cambridge University Press:  05 June 2009

R. S. Desowitz ,
P. Oothuman  and
D. A. Denham
R. S. Desowitz
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
P. Oothuman
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
D. A. Denham
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
Get access Rights & Permissions [Opens in a new window]

Abstract

In cats infected with normal, or irradiated, infective (L3) larvae of Brugia pahangi counterimmunoelectro-phoresis revealed the presence of antibody to soluble antigens derived from microfilariae, adults and infective larvae of the same parasite. Infected cats with a persistently high to moderate microfilaraemia gave positive precipitin reactions to L3, microfilarial and adult worm antigens. Cats which had become amicrofilaraemic had antibody to L3 and microfilarial antigens but not to adult worm antigen. Serum from cats inoculated with irradiated L3 larvae produced a precipitin reaction only to the L3 antigen.

Type
Research Papers
Information
Journal of Helminthology , Volume 52 , Issue 2 , June 1978 , pp. 127 - 130
Copyright
Copyright © Cambridge University Press 1978

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Denham, D. A., Ponnudurai, T., Nelson, G. S., Guy, F. and Rogers, R. (1972a) Studies with Brugia pahangi. I. Parasitological observations on primary infections of cats (Felis catus). International Journal for Parasitology, 2, 239–247.CrossRefGoogle ScholarPubMed
Denham, D. A., Ponnudurai, T., Nelson, G. S., Rogers, R. and Guy, F. (1972b) Studies with Brugia pahangi. II. The effect of repeated infection on parasite levels in cats. International Journal for Parasitology, 2, 401–407.CrossRefGoogle ScholarPubMed
Desowitz, R. S. and Hitchcock, J. C. (1974) Hyperendemic bancroftian filariasis in the Kingdom of Tonga: The application of the membrane filter concentration technique to an age-startified blood survey. American Journal of Tropical Medicine and Hygiene, 23, 877–879.CrossRefGoogle Scholar
Desowitz, R. S. and UNA, S. R. (1976) The detection of antibodies in human and animal filariasis by counterimmunoelectrophoresis with Dirofilaria immitis antigens. Journal of Helminthology, 50, 53–57.CrossRefGoogle ScholarPubMed
Ponnudurai, T., Denham, D. A., Nelson, G. S. and Rogers, R. (1974) Studies with Brugia pahangi. 4. Antibodies against adult and microfilarial stages. Journal of Helminthology, 48, 107–111.CrossRefGoogle ScholarPubMed
Sajidiman, H., Desowitz, R. S. and Darwis, F. (1975) Studies on filariasis in the Pacific: 5. Brugia malayi filariasis in treated and untreated populations of South Borneo. Southeast Asian Journal of Tropical Medicine and Public Health, 6, 190–194.Google ScholarPubMed
Wong, M. M. and Guest, M. F. (1969) Filarial antibodies and eosinophilia in human subjects in an endemic area. Transactions of the Royal Society of Tropical Medicine and Hygiene, 63, 796–800.CrossRefGoogle Scholar