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Studies with Brugia pahangi. 15. Cobalt 60 irradiation of the worm

Published online by Cambridge University Press:  05 June 2009

Pakeer Oothuman ,
D. A. Denham ,
P. B. McGreevy  and
G. S. Nelson
Pakeer Oothuman
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
D. A. Denham
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
P. B. McGreevy
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
G. S. Nelson
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
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Abstract

Infective larvae of Brugia pahangi were irradiated at 10, 25 or 45 krads by means of a Cobalt 60 source. In cats, 10 krads caused the worms to be stunted and sterile but allowed them to become 5th stage, migrate posterioly into the afferent lymphatic, and produce pathology.

25 krads prevented the worms from developing beyond the early fourth stage and from migrating away from the popliteal lymph node. No gross pathological reactions were evident. 45 krads produced the same effects as 25 krads but the longevity of the worms was much reduced.

Type
Research Papers
Information
Journal of Helminthology , Volume 52 , Issue 2 , June 1978 , pp. 121 - 126
Copyright
Copyright © Cambridge University Press 1978

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References

REFERENCES

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