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Studies on the Liver, Lung, Brain and Blood of Experimental Animals Infected with Toxocara canis

Published online by Cambridge University Press:  18 November 2009

B. Bisseru
B. Bisseru
Affiliation:
Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur
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Extract

Studies were carried out in mice and a monkey (paratenic hosts) and pathological lesions in mice have been described in liver, lung and brain with Toxocara larvae moving actively in the tissues causing damage (haemorrhages and necrosis) with encystment. In both mice and monkey there is essentially an eosinophilic response with lymphocytes and neutrophils also showing rise in the peripheral blood a few days after infection. In mice lymphocytes are the predominant tissue inflammatory cell.

Type
Research Papers
Information
Journal of Helminthology , Volume 43 , Issue 3-4 , September 1969 , pp. 267 - 272
Copyright
Copyright © Cambridge University Press 1969

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References

Beaver, P. C., Snyder, C. H., Carrera, G. M., Dent, J. G. and Lafferty, J. M., 1952.—“Chronic eosinophilia due to visceral larva migrans; report of a case.” Pediatrics, 9, 7.CrossRefGoogle Scholar
Brill, R., Churg, J. and Beaver, P. C., 1953.—“Allergic granulomatosis associated with visceral larva migrans; case report with autopsy findings of toxocara infection in child.” Ann. Jt Clin. Path., 23, 1208.CrossRefGoogle Scholar
Chaudhuri, R. N. and Saha, T. K., 1959.—“Tropical eosinophilia: experiments with Toxocara canis.” Lancet, 2, 493.CrossRefGoogle ScholarPubMed
Done, J. T., Richardson, M. D. and Gibson, T. E., 1960.—“Experimental visceral larva migrans in the pig.” Res. vet. Sci., 1, 133.CrossRefGoogle Scholar
Olson, L. J., 1961.—“Distribution of Toxocara canis larvae in normal mice and in mice infected with Toxocara, Ascaris lumbricoides or T. spiralis.” J. Parasit., 47, 18.Google Scholar
Olson, L. J., and Schulz, C. W., 1963.—“Some biochemical and immunological aspects of host-parasite relationships. Nematode-induced hyper-sensitivity reactions in guinea pigs: onset of eosinophilia and positive Schultz-Dale reactions following graded infections with Toxocara canis.” Ann. N. Y. Acad. Sci., 133, 440.CrossRefGoogle Scholar
Pike, H. H., 1960.—“Effect of diethylcarbamazine, oxophenarsine hydrochloride and piperazine citrate on Toxocara canis larvae in mice.” Expl Parasit., 9, 223.CrossRefGoogle ScholarPubMed
Roneus, O., 1963.—“Parasitic liver lesions in swine, experimentally produced by visceral larva migrans of T. cati.” Acta. Vet. Scandin., 4, 170.CrossRefGoogle Scholar
Smith, M. H. D., and Beaver, P. C., 1953.—“Persistence and distribution of Toxocara larvae in the tissues of children and mice.” Pediatrics, 12, 491.CrossRefGoogle ScholarPubMed
Sprent, J. F. A., 1952.—“On migratory behaviour of larvae of various ascaris species in white mice.” J. infect. Dis., 90, 165.CrossRefGoogle ScholarPubMed
Sprent, J. F. A., 1955.—“On the invasion of the central nervous system by nematodes. II. Invasion of the nervous system in ascariasis.” Parasitology, 45, 31.CrossRefGoogle ScholarPubMed