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Seroprevalence of Toxocara infection in children and environmental contamination of urban areas in Paraná State, Brazil

Published online by Cambridge University Press:  25 November 2011

S. Mattia ,
C.M. Colli ,
C.M. Adami ,
G.F. Guilherme ,
L. Nishi ,
G. Rubinsky-Elefant ,
A.A. Marchioro ,
M.L. Gomes  and
A.L. Falavigna-Guilherme
S. Mattia
Affiliation:
Laboratory of Environmental Parasitology, State University of Maringá, Maringá87020-900, Brazil
C.M. Colli
Affiliation:
Laboratory of Environmental Parasitology, State University of Maringá, Maringá87020-900, Brazil
C.M. Adami
Affiliation:
Laboratory of Environmental Parasitology, State University of Maringá, Maringá87020-900, Brazil
G.F. Guilherme
Affiliation:
Laboratory of Environmental Parasitology, State University of Maringá, Maringá87020-900, Brazil
L. Nishi
Affiliation:
Laboratory of Environmental Parasitology, State University of Maringá, Maringá87020-900, Brazil
G. Rubinsky-Elefant
Affiliation:
Laboratory of Environmental Parasitology, State University of Maringá, Maringá87020-900, Brazil
A.A. Marchioro*
Affiliation:
Laboratory of Environmental Parasitology, State University of Maringá, Maringá87020-900, Brazil
M.L. Gomes
Affiliation:
Laboratory of Environmental Parasitology, State University of Maringá, Maringá87020-900, Brazil
A.L. Falavigna-Guilherme
Affiliation:
Laboratory of Environmental Parasitology, State University of Maringá, Maringá87020-900, Brazil
*
* E-mail: [email protected]
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Abstract

The objectives of this study were to evaluate the contamination by eggs of Toxocara in sandy areas or grass lawns of outdoor recreation areas that are used by children, and the frequency of seroprevalence in children, from three cities of fewer than 45,000 inhabitants in Paraná, Brazil. From May 2005 to December 2007, five samples were taken from each of 13 sandy sites and 18 grass lawns, all from plazas and public schools. Blood samples from children aged 0–12 years were analysed by immunoassay for anti-Toxocara IgG. The soil samples were processed by floatation and sedimentation. Eggs of Toxocara spp. were present in 44.7% (38/85) of the samples from grassed areas and in 21.4% (15/70) of the sand samples. The lawns were 2.16 times more contaminated than the sand (P = 0.0009). However, the epidemiological variables showed no statistically significant difference between seropositive (36.8%; 130/353), and seronegative children. The rate of seropositivity was higher in children aged 0–5 years (P = 0.03), who were 1.94 times more likely to develop persistent wheezing (P = 0.02).

Type
Research Papers
Information
Journal of Helminthology , Volume 86 , Issue 4 , December 2012 , pp. 440 - 445
Copyright
Copyright © Cambridge University Press 2011

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References

Anaruma Filho, F., Chieffi, P.P., Correa, C.R.S., Camargo, E.D., Silveira, E.P.R., Aranha, J.J.B. & Ribeiro, M.C.S.A. (2002) Human toxocariasis: a seroepidemiological survey in the municipality of Campinas (SP), Brazil. Revista do Instituto de Medicina Tropical de São Paulo 44, 303–307.CrossRefGoogle ScholarPubMed
Avcioglu, H. & Balkaya, I. (2011) The relationship of public park accessibility to dogs to the presence of Toxocara species ova in the soil. Vector-Borne and Zoonotic Diseases 11, 177–180.CrossRefGoogle Scholar
Bass, J.L., Mehta, K.A., Glickman, L.T. & Eppes, B.M. (1983) Clinically inapparent Toxocara infection in children. New England Journal of Medicine 308, 723–724.Google ScholarPubMed
Beaver, P.C. (1956) Parasitological reviews – larva migrans. Experimental Parasitology 5, 587–621.CrossRefGoogle Scholar
Campos Júnior, D., Elefant, G.R., Silva, E.O.M., Gandolfi, L., Jacob, C.M.A., Tofeti, A. & Pratesi, R. (2003) Freqüência de soropositividade para antígenos de Toxocara canis em crianças de classes sociais diferentes. Revista da Sociedade Brasileira de Medicina Tropical 36, 509–513.CrossRefGoogle Scholar
Chieffi, P.P. & Mueller, E.E. (1976) Prevalência de parasitismo por Toxocara canis em cães e presença de ovos de Toxocara sp. no solo de localidade públicas da zona urbana do município de Londrina, estado de Paraná, Brasil. Revista de Saúde Pública 10, 367–372.CrossRefGoogle Scholar
Chorazy, M.L. & Richardson, D.J. (2005) A survey of environmental contamination with ascarid ova, Wallingford, Connecticut. Vector Borne Zoonotic Disease 5, 33–39.CrossRefGoogle ScholarPubMed
Coelho, R.A.L., Carvalho, J.R., Carvalho, L.B., Perez, E.P., Araki, K., Takeuchi, T., Ito, A., Aoki, T. & Yamasaki, H. (2005) Prevalence of toxocariasis in northeastern Brazil based on serology using recombinant Toxocara canis antigen. American Journal of Tropical Medicine and Hygiene 72, 103–107.CrossRefGoogle Scholar
Colli, C.M., Rubinsky-Elefant, G., Paludo, M.L., Falavigna, D.L.M., Guilherme, E.V., Mattia, S., Araujo, S.M., Ferreira, E.C., Previdelli, I.T.S. & Falavigna-Guilherme, A.L. (2010) Serological, clinical and epidemiological evaluation of toxocariasis in urban areas of south Brazil. Revista do Instituto de Medicina Tropical de São Paulo 52, 69–74.CrossRefGoogle ScholarPubMed
De Savigny, D.H., Voller, A. & Woodruff, A.W. (1979) Toxocariasis: serological diagnosis by enzyme immunoassay. Journal of Clinical Pathology 32, 284–288.CrossRefGoogle ScholarPubMed
Despommier, D. (2003) Toxocariasis: clinical aspects, epidemiology, medical ecology, and molecular aspects. Clinical Microbiology Reviews 16, 265–272.CrossRefGoogle ScholarPubMed
Dubná, S., Langrová, I., Jankovská, I., Vadlejch, J., Pekár, S., Nápravník, J. & Fechtner, J. (2007) Contamination of soil with Toxocara eggs in urban (Prague) and rural areas in the Czech Republic. Veterinary Parasitology 144, 81–86.CrossRefGoogle ScholarPubMed
Ferreira, L.F., Oliveira, E.L. & Camilo-Coura, L. (1976) Sobre a presença de ovos de Toxocara em praças da cidade do Rio de Janeiro. Revista da Sociedade Brasileira de Medicina Tropical 10, 51–54.CrossRefGoogle Scholar
Figueiredo, S.D.P., Taddei, J.A.A.C., Menezes, J.J.C., Novo, N.F., Silva, E.O.M., Cristóvão, H.L.G. & Cury, M.C.F.S. (2005) Estudo clínico-epidemiológico da toxocaríase em população infantil. Jornal de Pediatria 81, 126–132.CrossRefGoogle Scholar
Habluetzel, A., Traldi, G., Ruggeri, S., Attili, A.R., Scuppa, P., Marchetti, R., Menghini, G. & Esposito, F. (2003) An estimation of Toxocara canis prevalence in dogs, environmental egg contamination and risk of human infection in the Marche regions of Italy. Veterinary Parasitology 113, 243–252.CrossRefGoogle ScholarPubMed
IPARDES (2008) Instituto Paranaense de Desenvolvimento Econômico e Social. Available athttp://www.ipardes.gov.br (accessed accessed 7 February 2008).Google Scholar
Jacob, C.M.A., Pastorino, A.C., Peres, B.A., Melo, E.O., Okay, Y. & Oselka, G. (1994) Clinical and laboratorial features of visceral toxocariasis in infancy. Revista do Instituto de Medicina Tropical de São Paulo 36, 19–26.CrossRefGoogle ScholarPubMed
Leite, C.M.B., Bernardes, R.S. & Oliveira, S.A. (2004) Walkley–Black method for organic matter determination in soils contaminated by leachate. Revista Brasileira de Engenharia Agrícola Ambiental 8, 111–115.CrossRefGoogle Scholar
Lopez, M.L.A., Martin, G., Chamorro, M.D.C. & Alonso, J.M. (2005) Toxocariosis em niños de una región subtropical. Medicina 65, 226–230.Google Scholar
Matsuo, J. & Nakashio, S. (2005) Prevalence of fecal contamination in sandpits in public parks in Sapporo City, Japan. Veterinary Parasitology 128, 115–119.CrossRefGoogle ScholarPubMed
Paludo, L.M., Falavigna, D.L.M., Elefant, G.R., Gomes, L.G., Baggio, M.L.M., Amadei, L.B. & Falavigna-Guilherme, A.L. (2007) Frequency of Toxocara infection in children attended by the health public service of Maringá, South Brazil. Revista do Instituto de Medicina Tropical de São Paulo 49, 343–348.CrossRefGoogle ScholarPubMed
Pierangeli, N.B., Giayetto, A.L., Manacorda, A.M., Barbieri, L.M., Soriano, S.V., Veronesi, A., Pezzani, B.C., Minvielle, M.C. & Basualdo, J. (2003) Soil contamination with intestinal parasites in Neuquén, Patagonia, Argentina. Tropical Medicine and International Health 8, 259–263.CrossRefGoogle ScholarPubMed
Rey, L. (2001) Parasitologia. Parasitoses e doenças parasitarias do homem nas Américas e na África. 3rd edn.701 pp. Rio de Janeiro, Editora Guanabara Koogan S. A.Google Scholar
Roldán, H., Cavero, Y.A., Espinoza, Y.A., Jiménez, S. & Gutiérrez, C.A. (2010) Human toxocariasis: a seroepidemiological survey in the Amazonian city of Yurimaguas, Peru. Revista do Instituto de Medicina Tropical de São Paulo 52, 37–42.CrossRefGoogle ScholarPubMed
Rubinsky-Elefant, G., Shimizu, S.H., Sanches, M.C.A., Jacob, C.M.A. & Ferreira, A.W. (2006) A serological follow-up of toxocariasis patients after chemotherapy based on the detection of IgG, IgA and IgE antibodies by enzyme-linked immunosorbent assay. Journal of Clinical Laboratory Analysis 20, 164–172.CrossRefGoogle Scholar
Scaini, C.J., Toledo, R.N., Lovatel, R., Dionello, M.A., Gatti, F.A., Susin, L. & Signorini, V.R.M. (2003) Contaminação ambiental por ovos e larvas de helmintos em fezes de cães na área central do Balneário Cassino, Rio Grande do Sul. Revista da Sociedade Brasileira de Medicina Tropical 36, 617–619.CrossRefGoogle ScholarPubMed
Schantz, P.M. (1989) Toxocara larva migrans now. American Journal of Tropical Medicine and Hygiene 41, 21–34.CrossRefGoogle ScholarPubMed
Schantz, P.M., Meyer, D. & Glickman, L.T. (1979) Clinical, serologic, and epidemiologic characteristics of ocular toxocariasis. American Journal of Tropical Medicine and Hygiene 28, 24–28.CrossRefGoogle ScholarPubMed
Teixeira, C.R., Chieffi, P.P., Lescano, S.A.Z., Silva, E.O.M., Fux, B. & Cury, M.C. (2006) Frequency and risk factors for toxocariasis in children from a pediatric outpatient center in southeastern Brazil. Revista do Instituto de Medicina Tropical de São Paulo 48, 251–255.CrossRefGoogle ScholarPubMed
Tiyo, R., Guedes, T.A., Falavigna, D.L.M. & Falavigna-Guilherme, A.L. (2008) Seasonal contamination of public squares and lawns by parasites with zoonotic potential in Southern Brazil. Journal of Helminthology 81, 1–6.CrossRefGoogle Scholar