Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-03T00:51:13.622Z Has data issue: false hasContentIssue false
  • English
  • Français

The occurrence of Strongyloides ratti in the tissues of mice after percutaneous infection

Published online by Cambridge University Press:  18 November 2009

H. J. S. Dawkins ,
H. J. Thomason  and
D. I. Grove
H. J. S. Dawkins
Affiliation:
Department of Medicine, University of Western Australia, and the Repatriation General Hospital, Nedlands, Western Australia 6009, Australia
H. J. Thomason
Affiliation:
Department of Medicine, University of Western Australia, and the Repatriation General Hospital, Nedlands, Western Australia 6009, Australia
D. I. Grove
Affiliation:
Department of Medicine, University of Western Australia, and the Repatriation General Hospital, Nedlands, Western Australia 6009, Australia
Get access Rights & Permissions [Opens in a new window]

Abstract

The migration of infective larvae of Strongyloides ratti has been examined in C57B1/6 mice after percutaneous infection of the anterior abdominal wall. Lateral migration of larvae through the skin and subcutaneous tissues was not seen. Large numbers of larvae were recovered from the muscles between 2 and 24 hours after infection and larvae were seen in the cerebrospinal fluid 24 and 48 hours after infection. Insignificant numbers of larvae were seen in the blood, serosal cavities, liver, spleen, kidneys, brain or nasopharynx. Larvae arrived in the lungs between 24 and 72 hours after infection and worms were first noted in the small intestines at 48 hours. It is concluded that larvae migrate preferentially to the muscles and CSF before passing to the lungs, but the exact mode of travel is uncertain.

Type
Research Papers
Information
Journal of Helminthology , Volume 56 , Issue 1 , March 1982 , pp. 45 - 50
Copyright
Copyright © Cambridge University Press 1982

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Abadie, S. H. (1963) The life cycle of Strongyloides ratti. Journal of Parasitology, 49, 241–248.CrossRefGoogle ScholarPubMed
Ade, Y., Hattori, Y. & Tanaka, H. (1965a) Experimental observation on the parasitism of Strongyloides ratti in the case of isolation of the migration route in host. (Abstract). Japanese Journal of Parasitology, 14, 328. (In Japanese).Google Scholar
Abe, Y., Tanaka, H., Kagei, N. & Hori, E. (1965b) Experimental studies of the migration route of Strongyloides ratti (Abstract). Japanese Journal of Parasitology, 14, 367 (in Japanese).Google Scholar
Dawkins, H. J. S. & Grove, D. I.(1981) Kinetics of primary and secondary infections with Strongyloides ratti in mice. International Journal for Parasitology, 11, 89–96.CrossRefGoogle ScholarPubMed
Dawkins, H. J. S., Grove, D. I., Dunsmore, J. D. & Mitchell, G. F. (1980) Strongyloiiles ratti: susceptibility to infection and resistance to reinfection in inbred strains of mice as assessed by excretion of larvae. International Journal for Parasitology, 10, 125–129.CrossRefGoogle ScholarPubMed
Hattori, Y., Tada, I. & Nagano, K. (1968) A further study on the migration of Strongyloides ratti in host animals (Abstract). Japanese Journal of Parasitology, 17, 343 (in Japanese).Google Scholar
Spindler, L. A. (1958) The occurrence of the intestinal threadworms, Strongyloides ratti, in the tissues of rats following experimental percutaneous infection. Proceedings of the Helminthological Society of Washington, 25, 106–111.Google Scholar
Tada, I., Mimori, T. & Nakai, M. (1979) Migration route of Strongyloides ratti in albino ruts. Japanese Journal of Parasitology, 28, 219–227.Google Scholar
Wertheim, G. & Lengy, J. (1965) Growth and development of Strongyloides ratti Sandground, 1925, in the albino rat. Journal of Parasitology, 51, 636–639.CrossRefGoogle ScholarPubMed