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Extraintestinal migration of Pharyngostomum cordatum metacercariae in experimental rodents

Published online by Cambridge University Press:  12 April 2024

E.H. Shin ,
J.Y. Chai  and
S.H. Lee
E.H. Shin
Affiliation:
Department of Parasitology, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul National University Medical Research Center, Seoul 110-799, Korea
S.H. Lee
Affiliation:
Department of Parasitology, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul National University Medical Research Center, Seoul 110-799, Korea
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Abstract

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Extraintestinal migration patterns of Pharyngostomum cordatum (Digenea: Neodiplostomidae) were studied in experimental rodents such as mice, rats, and hamsters. When metacercariae isolated from grass snakes were infected orally to rodents, they penetrated the intestinal wall at days 2–3 post-infection (p.i.) and were discovered mainly in the diaphragm, intercostal muscles, and vital organ such as the lungs at days 7–28 p.i., without morphological changes. Interestingly, from several rodents which died suddenly at days 2–9 p.i., small to considerable numbers of metacercariae were found, not only in the lungs, but also in the heart and brain. Within the tissues, worms were freely motile until day 7 p.i., but later they were surrounded by host cells, and finally tissue cysts were formed. When metacercariae harvested from the snakes and intercostal muscles of rodents were infected orally to cats, they developed into adult flukes in the small intestine. The results show that P. cordatum undergoes considerable extraintestinal migration including the vital organs of its rodent hosts.

Type
Research Article
Information
Journal of Helminthology , Volume 75 , Issue 3 , September 2001 , pp. 285 - 290
Copyright
Copyright © Cambridge University Press 2001

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