Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-10T02:38:17.414Z Has data issue: false hasContentIssue false
  • English
  • Français

Experimental Trichinella spiralis infection in the ferret, Mustela putorius furo

Published online by Cambridge University Press:  18 November 2009

William C. Campbell ,
Lyndia Slayton Blair ,
Fan-Yao Kung  and
Debra Vislocky Ewanciw
William C. Campbell
Affiliation:
Merck Institute for Therapeutic Research, Rahway, New Jersey, USA
Lyndia Slayton Blair
Affiliation:
Merck Institute for Therapeutic Research, Rahway, New Jersey, USA
Fan-Yao Kung
Affiliation:
Merck Institute for Therapeutic Research, Rahway, New Jersey, USA
Debra Vislocky Ewanciw
Affiliation:
Merck Institute for Therapeutic Research, Rahway, New Jersey, USA
Get access Rights & Permissions [Opens in a new window]

Abstract

Laboratory ferrets (Mustela putorius furo) were each inoculated with 500 larvae of a strain of Trichinella spiralis that had been passaged in mice for many generations. The recovery of adult worms from ferrets on Days 4 and 7 of infection represented a mean of 32% of the inoculum, with most of the worms being in the anterior three quarters of the small intestine. Larvae subsequently became encysted in the ferret musculature, with the diaphragm alone yielding as many as 5,750 larvae upon digestion.

For comparative purposes, mice were each inoculated with 200 T. spiralis from the same batch of larvae. The recovery of adult worms from mice represented a mean of 54% of the inoculum. An abrupt decline in worm population, typical of infections in the mouse, was observed in both mouse and ferret hosts; in neither species had the decline begun on Day 7 of infection, but it had clearly begun by Day 11 and was essentially ended by Day 14.

Type
Research Papers
Information
Journal of Helminthology , Volume 56 , Issue 1 , March 1982 , pp. 55 - 58
Copyright
Copyright © Cambridge University Press 1982

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Blair, L. S. & Campbell, W. C. (1971) Reversibility of thiabendazole-induced sterilization of Trichinella spiralis. Wiadomosci Parazytologiczne, 17, 641–644.Google ScholarPubMed
Campbell, W. C. & Cuckler, A. C. (1966) Further studies on the effect of thiabendazole on trichinosis in swine, with notes on the biology of the infection. Journal of Parasitology, 52, 260–279.CrossRefGoogle Scholar
Cironeanu, I. (1974) Trichinellosis in domestic and wild animals in Rumania. In: Kim, C. W. (editor) Trichinellosis, Intext Educational Publishers, New York, pp. 549–555.Google Scholar
Cordero Del Campillo, M., Martinez Fernandez, A. & Aller Gancedo, B. (1970) Some facts concerning the epizootiology of trichinellosis in Spain. Wiadomosci Parazytologiczne, 16, 100–108.Google ScholarPubMed
Cram, E.B.(1941) Trichinella spiralis. In: Chitwood, B.G. & Chitwood, M.B. (Editors) An Introduction to Nematology, Chitwood, Babylon, New York, Section II, Part 2, pp. 316–318.Google Scholar
Hörning, B. (1976) Trichinella spiralis und Trichinellose in der Schweiz. Hausdruckerei Institute für exakte Wissenschafter, Bern, 1976, 41 pp.Google Scholar
Merkushev, A. V. (1970) Trichinosis in the Union of Soviet Socialist Republic. In: Gould, S. E. (editor) Trichinosis in man and animals. Charles C. Thomas, Springfield, Illinois, pp. 449–456.Google Scholar
Walker, E. P. (1964) Mammals of the world. Volume II. Johns Hopkins Press, Baltimore, USA, p. 1194.Google Scholar