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Experimental Brugia pahangi and B. malayi infections of callitrichid primates

Published online by Cambridge University Press:  05 June 2009

D. A. Denham ,
R. R. Suswillo  and
C. M. Hetherington
D. A. Denham
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, England
R. R. Suswillo
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, England
C. M. Hetherington
Affiliation:
National Institute of Medical Research, The Ridgeway, London, NW7 1AA, England
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Abstract

The callitrichid primates, Callithrix jacchus jacchus (the marmoset) and Saguinus labiatus (the tamarin) were inoculated with infective larvae of Brugia malayi and B. pahangi. Microfilaraemia at low levels developed in 3 out of 4 C. j. jacchus infected with B. malayi and living or dead adult worms found in all 4. Only one of 4 C. j. jacchus became microfilaraemic (mf + ve) when given B. pahangi and adults were found in two. Of 4 S. labiatus given B. pahangi one became very lightly mf + ve and adults were found in 3. It is concluded that these animals are not suitable hosts for chemotherapeutic experiments.

Keywords

Brugia malayiBrugia pahangicallitrichid primatesCallithrix jacchus jacchusSaguinus labiatusmarmosetstamarins
Type
Research Article
Information
Journal of Helminthology , Volume 63 , Issue 2 , June 1989 , pp. 84 - 86
Copyright
Copyright © Cambridge University Press 1989

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References

REFERENCES

Campbell, J. R., Soekartono, Purnomo, Atmosoedjono, S. & Marwoto, H. (1986) Experimental Wuchereria kalimantani infection in the leaf monkey, Presbytis cristatus. Annals of Tropical Medicine and Parasitology, 80, 141–142.CrossRefGoogle Scholar
Cross, J. H., Partono, F., Hsu, M. Y., Ash, L. R. & Oemijati, S. (1979) Experimental transmission of Wuchereria bancrofti to monkeys. American Journal of Tropical Medicine and Hygiene, 28, 56–66.CrossRefGoogle ScholarPubMed
Denham, D. A. (1974) Studies with Brugia pahangi 8. Infections inMacaca mulatta. Journal of Helminthology, 48, 265–267.CrossRefGoogle ScholarPubMed
Denham, D. A. (1982) Experience with a screen for macrofilaricidal activity using transplanted adult Brugia pahangi in the peritoneal cavities of Meriones unguiculatus. In “Animal Models in Parasitology” pp. 93–104 ed. Owen, D. G., The Macmillan Press, London.CrossRefGoogle Scholar
Dennis, D. T. & Kean, B. H. (1971) Isolation of microfilariae: report of a new method. Journal of Parasitology, 57, 1146–1147.CrossRefGoogle ScholarPubMed
Harinasuta, C, Sucharit, S. & Choochote, W. (1981) The susceptibility of leaf monkeys to bancroftian filariasis in Thailand. Southeast Asian Journal of Tropical Medicine and Public Health, 12, 581–589.Google ScholarPubMed
Lian, Z. G., Chen, Z., Chai, S. & Liu, X. J. (1973) [Observations on the experimental transmission of Brugia malayi from man to monkeys and cat.] Acta Zoologica Sinica, 19, 213–219, (In Chinese).Google Scholar
Palmieri, J. R., Connor, D. H., Purnomo, , Dennis, D. T. & Marwoto, H. (1982) Experimental infection of Wuchereria bancrofti in the silvered leaf monkey Presbytis cristatus Eschscholtz, 1821. Journal of Helminthology, 56, 243–245.CrossRefGoogle ScholarPubMed
Palmieri, J. R., Connor, D. H., Purnomo, & Marwoto, H. A. (1983) Bancroftian filariasis. Wuchereria bancrofti infection in the silvered leaf monkey (Presbytis cristatus). American Journal of Pathology, 112, 383–386.Google ScholarPubMed
Sucharit, S., Harinasuta, C. & Choochote, W. (1982) Experimental transmission of subperiodic Wuchereria bancrofti to the leaf monkey (Presbytis melalophos), and its periodicity. American Journal of Tropical Medicine and Hygiene, 31, 599–601.CrossRefGoogle Scholar
Suswillo, R. R., Denham, D A. & Mcgreevy, P. B. (1982) The number and distribution of Brugia pahangi in cats at different times after a primary infection. Acta Tropica, 39, 151–156.Google ScholarPubMed
Wong, M. M., Guest, M. F., Lim, K. C. & Sivanandum, S. (1977) Experimental Brugia malayi infections in the rhesus monkey. Southeast Asian Journal of Tropical Medicine and Public Health, 8, 265–273.Google ScholarPubMed
Wong, M. M. & Lim, K. C. (1975) Susceptibility of the “bush baby” (Galago crassicaudatus panganiensis) to Brugia malayi and B. pahangi. Journal of Parasitology, 61, 598.CrossRefGoogle ScholarPubMed