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The effect of Trichinella spiralis on the rate of clearance of 51 Cr-labelled sheep red blood cells and 125I-polyvinyl pyrrolidone from the bloodstream of mice

Published online by Cambridge University Press:  05 June 2009

Nagwa A. N. Aboul-Atta ,
M. W. Steward  and
D. A. Denham
Nagwa A. N. Aboul-Atta
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT
M. W. Steward
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT
D. A. Denham
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT
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Abstract

Mice infected for one to eight weeks with Trichinella spiralis cleared either 51Cr-labelled sheep red blood cells (SRBC) or I-polyvinyl pyrrolidone (PVP) given intravenously. PVP was cleared more rapidly from the blood of mice infected for one week than from uninfected mice with older infections which behaved in a similar manner to the controls. SRBC were consistently cleared faster from the blood of mice infected for one week than from normal mice. If the infections were older than this a more rapid clearance was also demonstrated as long as the infections were reasonably heavy.

Type
Research Article
Information
Journal of Helminthology , Volume 55 , Issue 4 , December 1981 , pp. 287 - 293
Copyright
Copyright © Cambridge University Press 1981

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References

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