Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-23T22:29:39.287Z Has data issue: false hasContentIssue false
  • English
  • Français

The Development of Acquired Resistance and Age Resistance to Nematodirus battus in the Laboratory Rabbit

Published online by Cambridge University Press:  18 November 2009

G. J. Gallie
G. J. Gallie
Affiliation:
Parasitoiogy Department, Moredun Research Institute, Gilmerton, Edinburgh 9
Get access Rights & Permissions [Opens in a new window]

Extract

Four groups of 8 rabbits were infected with a range of doses of N. bath's larvae. The percentage recoveries of worms from groups receiving 100 and 1000 larvae were significantly greater than those from groups receiving 10000 and 50000 larvae. It is suggested that the worm population density is dependent on the degree of host response stimulated by the initial larval dose.

Experience of a chemically abbreviated patent infection of N. batlus gave significant protection to a group of 8 rabbits against establishment of worms from subsequent challenge compared with inexperienced controls.

Rabbits aged 5 months and 11 weeks were as susceptible to the establishment of worms as rabbits aged 7½ weeks; but age resistance vas manifested by the greater proportion of worms which developed to the fifth stage in the worm populations of the youngest group than in the other 2 groups.

Type
Research Article
Information
Journal of Helminthology , Volume 47 , Issue 4 , December 1973 , pp. 369 - 376
Copyright
Copyright © Cambridge University Press 1973

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Brunsdon, R.V., 1963.—“Nematodirus infestation in lambs: the importance of prepatent infestation in the stimulation of resistance.” N.Z. vet. J., 11 107–112.Google Scholar
Donald, A.D., Dineen, J. K., Turner, J.H. and Wagland, B. M., 1964.—“The dynamics of the host-parasite relationship. I. Nematodirus spathiger infection in sheep.” Parasitology, 54, 527–544.CrossRefGoogle ScholarPubMed
Gallie, G.J., 1972.—“Development of the parasitic stages of Nematodirus battes in the laboratory rabbit.” Parasitology, 64, 293–304.CrossRefGoogle Scholar
Gibson, T. E., 1959a.—“The development of resistance by sheep to infection with the nematodes Nematodirus filicollis and Nematodirus ballus.” Br. vet. J., 115, 120–123Google Scholar
Gibson, T. E., 1959b.—“Controlled tests with bephenium hydroxynapthoate as an anthelmintic against Nematodirus battes in sheep.” Vet. Rec., 71, 949–950.Google Scholar
Gibson, T. E., and Everett, G., 1963.—“The development of resistance by sheep to the nematode Nematodirus balfus.” Br. vet. J., 119, 214–218.CrossRefGoogle Scholar
Haley, A.J. and Parker, J.C., 1961.—“Effect of population density on adult worm survival in primary Nippostrongylus brasiliensis infections in the rat.” Proc. helm. Soc. Wash., 28, 176–180.Google Scholar
Jenkins, D.C. and Phiillipson, R.F., 1971.—“The kinetics of repeated low-level infections of Nippostrongylus brasiliensis in the laboratory rat.” Parasitology, 62, 457–465.CrossRefGoogle ScholarPubMed
Rawes, D.A. and Scarnell, J., 1959.—“Bephenium hydroxynapthoate-its activity against Nematodirus and other trichostrongylid nematodes in lambs.” Vet. Rec., 71, 645–650.Google Scholar
Sandground, J.H., 1929.—“consideration of the relation of host-specificity of helminths and other metazoan parasites to the phenomena of age resistance and acquired immunity.” Parasitology, 21, 227–255.CrossRefGoogle Scholar
Sturrock, R. F., 1963.—“Observations on the use of Trichostrongylus colubriformis (Nematoda) infections of guinea-pigs for laboratory experiments.” Parasitology, 53, 189–109.CrossRefGoogle Scholar