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A bolus for the administration to cattle of metacercariae of the liver fluke Fasciola hepatica

Published online by Cambridge University Press:  05 June 2009

S.J. Andrews ,
S. McGonigle ,
A.M. Smith ,
J.P. Dalton ,
D. Clery  and
G. Mulcahy
S.J. Andrews
Affiliation:
Mallinckrodt Veterinary Ltd, Breakspear Road South, Harefield, Uxbridge, Middlesex, UB9 6LS, UK
S. McGonigle
Affiliation:
School of Biological Sciences, Dublin City University, Dublin 9,Ireland
A.M. Smith
Affiliation:
School of Biological Sciences, Dublin City University, Dublin 9,Ireland
J.P. Dalton
Affiliation:
School of Biological Sciences, Dublin City University, Dublin 9,Ireland
D. Clery
Affiliation:
Department of Veterinary Microbiology and Parasitology, University College Dublin, Shelbourne Road, Ballsbridge, Dublin 4, Ireland
G. Mulcahy
Affiliation:
Department of Veterinary Microbiology and Parasitology, University College Dublin, Shelbourne Road, Ballsbridge, Dublin 4, Ireland
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Abstract

A gelatin-agar bolus, designed and developed for the administration of metacercariae of the liver fluke Fasciola hepatica, was evaluated in adult Holstein Friesian cattle. The metacercariae, enclosed within a gelatin capsule, were placed inside the bolus and delivered to each animal using an oesophageal balling gun. At slaughter, 13 weeks after challenge, an average of 25% of the challenge dose was recovered from each liver. This percentage recovery is similar to that obtained with other known methods. The new bolus, however, offers improved handling qualities. In addition, the bolus also has potential for improving a number of other techniques including those for the administration of other parasites, compounds or chemotherapeutic agents.

Type
Research Note
Information
Journal of Helminthology , Volume 69 , Issue 2 , June 1995 , pp. 165 - 167
Copyright
Copyright © Cambridge University Press 1995

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References

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