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Amino acid metabolism in Ancylostoma ceylanicum and Nippostrongylus brasiliensis*

Published online by Cambridge University Press:  05 June 2009

Govind Singh ,
Suman Gupta ,
J. C. Katiyar  and
V. M. L Srivastava
Govind Singh
Affiliation:
Divisions of Biochemistry,Central Drug Research Institute, Lucknow 226001, India
Suman Gupta
Affiliation:
Parasitology, Central Drug Research Institute, Lucknow 226001, India
J. C. Katiyar
Affiliation:
Parasitology, Central Drug Research Institute, Lucknow 226001, India
V. M. L Srivastava*
Affiliation:
Divisions of Biochemistry,Central Drug Research Institute, Lucknow 226001, India
*
†Author to whom correspondence should be addressed.
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Abstract

Ancylostoma ceylanicum and Nippostrongylus brasiliensis decarboxylated most of the amino acids examined, but only a few at signficant rates. The former nematode in general possessed higher activites. Striking differences between the two parasites were, however, noticed regarding the metabolism of some of the amino acids. For instance, while alanine followed by asparate produced highest amounts of 14CO2in the presence of A. ceylanicum, proline exhibited maximum decarboxlation in case of N. brasiliensis. Tyrosine, on the other hand, did not libreate detectable CO2with either parasite. Likewise, although large number of amino acids underwent transmination with 2-oxoglutarate, only some of them elicited appreciable activity for any two parasites.

Keywords

Ancylostoma ceylanicumNippostrongylus brasiliensisamino acidstransaminationdecarboxylation
Type
Research Papers
Information
Journal of Helminthology , Volume 61 , Issue 1 , March 1987 , pp. 84 - 88
Copyright
Copyright © Cambridge University Press 1987

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Footnotes

*

C.D.R.I. Communication No. 3588.

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