Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-07T15:48:04.924Z Has data issue: false hasContentIssue false
  • English
  • Français

The transmission of an avian filarioid Cardiofilaria nilesi to the jird, Meriones unguiculatus

Published online by Cambridge University Press:  05 June 2009

G. L. Chiang ,
W. H. Cheong ,
K. L. Eng  and
W. A. Samarawickrema
G. L. Chiang
Affiliation:
Division of Medical Entomology, Institute for Medical Research, Kuala Lumpur, Malaysia
W. H. Cheong
Affiliation:
Division of Medical Entomology, Institute for Medical Research, Kuala Lumpur, Malaysia
K. L. Eng
Affiliation:
Division of Medical Entomology, Institute for Medical Research, Kuala Lumpur, Malaysia
W. A. Samarawickrema
Affiliation:
Division of Medical Entomology, Institute for Medical Research, Kuala Lumpur, Malaysia
Get access Rights & Permissions [Opens in a new window]

Abstract

This paper reports the experimental transmission of a bird parasite into jirds. Infective larvae of Cardiofilaria nilesi obtained from laboratory colonized Coquillettidia crassipes mosquitoes which had fed on an infected chicken were inoculated subcutaneously into jirds. The number of larvae per jird varied from 10 to 228. Microfilaraemia appeared 22 to 89 days after inoculation of the infective larvae. Experiments were carried out with 24 jirds through six generations extending over a period of 22 months and 17 produced patent infections. At present 8 infected jirds are being maintained in the laboratory; their patent periods ranging from 6 to 13 months. However, the longest patent period observed was about thirteen months. The percentage of adults recovered in autopsied jirds ranged from 0 to 40 with an average of 16. The chicken showed a microfilarial periodicity with the peak microfilarial density around 2200 hours. However, in jirds there was a change in sub-periodicity. This model in the jird may be very useful for the screening of filaricides and in immunological work.

Keywords

Cardiofilaria nilesiMeriones unguiculatustransmission
Type
Research Papers
Information
Journal of Helminthology , Volume 61 , Issue 4 , December 1987 , pp. 349 - 353
Copyright
Copyright © Cambridge University Press 1987

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Chiang, G. L., Cheong, W. H., Samarawickrema, W. A. & Eng, K. L. (1986a) Laboratory colonization and life cycle of Coquillettidia crassipes Vanderwulp 1884 in Malaysia. Journal of the American Mosquito Control Association, 2, 545–547.Google Scholar
Chiang, G. L., Samarawickrema, W. A., Eng, K. L. & Cheong, W. H. (1986b) Field studies on the surveillance of Coquillettidia crassipes (Vanderwulp) and the isolation of a strain of Cardiofilaria in Peninsular Malaysia. Annals of Tropical Medicine and Parasitology, 80, 235–244.CrossRefGoogle Scholar
Dissanaike, A. S. & Fernando, M. A. (1965) Cardiofilaria nilesi n. sp., recovered from a chicken experimentally infected with infective larvae from Mansonia crassipes. Journal of Helminthology, 39, 151–158.Google Scholar
Gooneratne, B. M. W. (1969) The development of Cardiofilaria nilesi in laboratory bred Aedes togoi. Annals of Tropical Medicine and Parasitology, 63, 337–339.Google Scholar
Laing, A. B. G. (1959) The dusky leaf monkey (Presbytis obscurus) as a natural host of Wuchereria malayi in Malaya. Transactions of the Royal Society of Tropical Medicine and Hygiene, 53, 213–214.CrossRefGoogle Scholar
Mak, J. W., Chiang, G. L. & Cheong, W. H. (1984a) Cardiofilaria nilesi (Filarioidea: Onchocercidae) infection in chickens in Peninsular Malaysia. Tropical Biomedicine, 1, 115–120.Google Scholar
Mak, J. W., Lim, P. K. C. & Sim, B. K. L. (1984b) The periodicity of Brugia malayi in a naturally infected Macaca fascicularis and experimentally infected M. fascicularis and Presbytis melalophos. Tropical Biomedicine, 1, 15–19.Google Scholar
Mcghee, R. B. (1950) The ability of the avian malaria parasite, Plasmodium lophurae to infect erythrocytes of distantly related species of animals. American Journal of Hygiene, 52, 42–47.Google ScholarPubMed
Mcghee, R. B. (1951) The adaptation of an avian malaria parasite Plasmodium lophurae to a continuous existence in infant mice. Journal of Infective Diseases, 88, 86–97.Google Scholar
Niles, W. J. (1962) Natural infections of developing animal filariae in the fat body of Mansonia crassipes. Transactions of the Royal Society of Tropical Medicine and Hygiene, 56, 437–438.CrossRefGoogle Scholar
Niles, W. J. (1966) Mansonia crassipes a vector of bird filarioids in Ceylon. Ceylon Journal of Medical Science, 15, 41–44.Google Scholar
Niles, W. J. & Kulasiri, C. de S. (1970) Studies on Cardiofilaria nilesi in experimental chicken. Ceylon Journal of Medical Science, 19, 18–28.Google Scholar
Sasa, M. & Tanaka, H. (1974) A statistical method for comparison and classification of the microfilarial periodicity. Japanese Journal of Experimental Medicine, 44, 321–346.Google ScholarPubMed
Sucharit, S., Harinasuta, C. & Choochote, W. (1982) Experimental transmission of subperiodic Wuchereria bancrofti to the leaf monkey (Presbytis melalophos), and its periodicity. American Society of Tropical Medicine and Hygiene, 33, 599–601.Google Scholar
Tanaka, H. (1981) Periodicity of microfilariae of human filariasis analysed by a trigonometric method (Aikat and Das). Japanese Journal of Experimental Medicine, 51, 97–103.Google ScholarPubMed