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First case of human Gongylonema pulchrum infection in Slovenia

Published online by Cambridge University Press:  22 July 2019

U. Kramar
Affiliation:
National Laboratory of Health, Environment and Food, Maribor, Slovenia
M. Skvarč
Affiliation:
Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
M. Logar
Affiliation:
Department of Infectious Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia
S. Islamović
Affiliation:
Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
M. Kolenc
Affiliation:
Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
B. Šoba*
Affiliation:
Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
*
Author for correspondence: B. Šoba, E-mail: [email protected]

Abstract

Nematodes of the genus Gongylonema infect a wide range of mammals worldwide but are only sporadically reported in humans. We describe a case of human infection with Gongylonema pulchrum in a 41-year-old man. The patient extracted the nematode from the submucosa under his tongue and correctly self-diagnosed the infection with the help of the Google search engine. In the laboratory, the collected nematode was confirmed as G. pulchrum microscopically by morphological analysis and genetically by amplifying and sequencing the parasite's rDNA. This is the first report of human G. pulchrum infection in Slovenia.

Type
Short Communication
Copyright
Copyright © Cambridge University Press 2019 

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Footnotes

*

Current address: Jesenice General Hospital, Jesenice, Slovenia.

References

Allen, JD and Esquela-Kerscher, A (2013) Gongylonema pulchrum infection in a resident of Williamsburg, Virginia, verified by genetic analysis. The American Journal of Tropical Medicine and Hygiene 89, 755757.Google Scholar
Amászta, M, Holló, F, Miskolczy, L and Stróbl, I (1973) The 1st case of human gongylonematosis in Hungary. Orvosi Hetilap 114, 22372238 (in Hungarian).Google Scholar
Ayala, MA and Yencha, MW (2012) Gongylonema: A parasitic nematode of the oral cavity. Archives of Otolaryngology – Head & Neck Surgery 138, 10821084.Google Scholar
Battistelli-Lux, C (2013) Buccal infection with Gongylonema pulchrum: An indigenous case in France. Annales de Dermatologie et de Vénéréologie 140, 623627 (in French).Google Scholar
Eberhard, ML and Busillo, C (1999) Human Gongylonema infection in a resident of New York City. The American Journal of Tropical Medicine and Hygiene 61, 5152.Google Scholar
Gefter, VA and Nemirovskaia, OI (1965) Human gongylonematosis. Meditsinskaia Parazitologiia i Parazitarnye Bolezni 34, 158163 (in Russian).Google Scholar
Grinberg, AI (1968) A case of human gongylonematosis. Meditsinskaia Parazitologiia i Parazitarnye Bolezni 37, 243 (in Russian).Google Scholar
Halajian, A, Eslami, A, Salehi, N, Ashrafi-Helan, J and Sato, H (2010) Incidence and genetic characterization of Gongylonema pulchrum in cattle slaughtered in Mazandaran Province, northern Iran. Iranian Journal of Parasitology 5, 1018.Google Scholar
Haruki, K, Furuya, H, Saito, S, Kamiya, S and Kagei, N (2005) Gongylonema infection in man: A first case of gongylonemosis in Japan. Helminthologia 42, 6366.Google Scholar
Huang, Q, Wang, J, Yang, T and Liu, Y (2016) Multiple Gongylonema pulchrum worms in a human esophagus. Endoscopy 48(Suppl. 1), e2425.Google Scholar
Illescas-Gómez, MP, Rodriguez Osorio, M, Gómez Garcia, V and Gómez Morales, MA (1988) Human Gongylonema infection in Spain. The American Journal of Tropical Medicine and Hygiene 38, 363365.Google Scholar
Jelinek, T and Löscher, T (1994) Human infection with Gongylonema pulchrum: A case report. Tropical Medicine and Parasitology 45, 329330.Google Scholar
Libertin, CR, Reza, M, Peterson, JH, Lewis, J and Hata, DJ (2017) Human Gongylonema pulchrum infection: Esophageal symptoms and need for prolonged albendazole therapy. The American Journal of Tropical Medicine and Hygiene 96, 873875.Google Scholar
Liu, GH, Jia, YQ, Wang, YN, Zhao, GH and Zhu, XQ (2015) The complete mitochondrial genome of the gullet worm Gongylonema pulchrum: Gene content, arrangement, composition and phylogenetic implications. Parasites & Vectors 8, 100.Google Scholar
Makouloutou, P, Rana, HB, Adhikari, B, Devkota, B, Dhakal, IP and Sato, H (2013a) A distinct genetic population of Gongylonema pulchrum from water buffaloes in Nepal. The Journal of Parasitology 99, 669676.Google Scholar
Makouloutou, P, Setsuda, A, Yokoyama, M, et al. (2013b) Genetic variation of Gongylonema pulchrum from wild animals and cattle in Japan based on ribosomal RNA and mitochondrial cytochrome c oxidase subunit I genes. Journal of Helminthology 87, 326335.Google Scholar
Molavi, GH, Massoud, J and Gutierrez, Y (2006) Human Gongylonema infection in Iran. Journal of Helminthology 80, 425428.Google Scholar
Pesson, B, Hersant, C, Biehler, JF, Abou-Bacar, A, Brunet, J, Pfaff, AW, Ferté, H and Candolfi, E (2013) First case of human gongylonemosis in France. Parasite (Paris, France) 20, 5.Google Scholar
Ryšavy, B, Šebek, Z and Tenora, F (1969) The finding of Gongylonema pulchrum Molin, 1857 (Nematoda) in man. Folia Parasitologica 16, 66.Google Scholar
Sato, H, Suzuki, K, Osanai, A, Kamiya, H and Furuoka, H (2006) Identification and characterization of the threadworm, Strongyloides procyonis, from feral raccoons (Procyon lotor) in Japan. The Journal of Parasitology 92, 6368.Google Scholar
Setsuda, A, Da, N, Hasegawa, H, Behnke, JM, Rana, HB, Dhakal, IP and Sato, H (2016) Intraspecific and interspecific genetic variation of Gongylonema pulchrum and two rodent Gongylonema spp. (G. aegypti and G. neoplasticum), with the proposal of G. nepalensis n. sp. for the isolate in water buffaloes from Nepal. Parasitology Research 115, 787795.Google Scholar
Tang, H and Ng, JH (2006) Googling for a diagnosis – use of Google as a diagnostic aid: internet based study. British Medical Journal (Clinical research ed.) 333, 11431145.Google Scholar
Urch, T, Albrecht, BC, Büttner, DW and Tannich, E (2005) Human infection with Gongylonema pulchrum. Deutsche Medizinische Wochenschrift 130, 25662568 (in German).Google Scholar
Varcasia, A, Scala, A, Zidda, A, Cabras, PA, Gaglio, G, Tamponi, C, Pipia, AP, Setsuda, A and Sato, H (2017) First record of Gongylonema nepalensis in domestic and wild ruminants in Europe. Veterinary Parasitology 246, 1118.Google Scholar
Waisberg, V, Dos Santos Lima, W and Vasconcelos-Santos, DV (2018) Intraocular Gongylonema infection: first case in humans. Ocular Immunology and Inflammation 26, 595597.Google Scholar
Weber, G and Mache, K (1973) Skin manifestations in Gongylonema pulchrum, first human case in Germany. Hautarzt 24, 286288 (in German).Google Scholar
Wilson, ME, Lorente, CA, Allen, JE and Eberhard, ML (2001) Gongylonema infection of the mouth in a resident of Cambridge, Massachusetts. Clinical Infectious Diseases 32, 13781380.Google Scholar
Xiaodan, L, Zhensheng, W, Ying, H, Hongwei, L, Jianqiu, J, Peiru, Z, Sha, S and Zhimin, Y (2018) Gongylonema pulchrum infection in the human oral cavity: A case report and literature review. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 125, e4953.Google Scholar