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Acquired Immunity to Trichostrongylus axei in Lambs: Investigations of the Development of Immune Competence

Published online by Cambridge University Press:  05 June 2009

J. G. Ross
Affiliation:
Veterinary Research Laboratories, Stormont, Belfast

Extract

Investigations are described in which lambs were given either 1,000 or 5,000 3rd stage infected larvae of T. axei at 2, G, or 10 weeks age and were subsequently challenged with 200,000 3rd stage larvae at either 5 or 7 months of age. The immunity acquired following primary infection was manifest by a reduction in the numbers and size of the worms developing after challenge infection.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1970

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References

REFERENCES

Gibson, T. E., 1952.— “The development of acquired resistance by sheep to infestation with the nematode Trichostrongylus axei”. J. Helminth., 26, 4353.CrossRefGoogle Scholar
Lopez, V. and Urquhart, G. M., 1967.— “The immune response of Merino sheep to Hacmonchus contortus infection”. Proc. 3rd Inst. conf. Wld. Ass.Adv. Vet. Parasitol. Lyon, 153.Google Scholar
Manton, V. J. A., Peacock, R., Povnter, D., Silverman, F. A. and Terry, R. J., 1962.— “The influence of age or naturally acquired resistance to Haemonchus contortus in lambs”. Res. Vet. Sci., 3, 308314.CrossRefGoogle Scholar
Ross, J. G., 1965.— “The role of the larval stages of Haemonchus placet infections of cattle in immunity”. J. Helminth., 37, 359368.CrossRefGoogle Scholar
Ross, J. G., 1965.— “Anthelmintic field trials in sheep. A comparison of Haloxon and Phenothiazine treatment in ewes and lambs.Rec. agric. Res. Minist. Agric. Nth. Ire., 14, 4347.Google Scholar
Sinha, P. K., 1967.— “Active immunity against Trichostrongylus axei in sheep and rabbits”. Am. J. vet. Res., 28, 793798.Google ScholarPubMed
Todd, J. R. and Ross, J. G., 1968.— “Biochemical and hematological changes in the blood of normal sheep following repeated phlebotomy”. Br. vet. J., 124, 353.CrossRefGoogle ScholarPubMed
Urquhart, G. M., Jarrett, W. F. H., Jennings, F. W., Mcintyre, W. I. M., Mulligan, W. and Sharp, M. C. C., 1966a.— “Immunity to Haemonchus contortus infection. Failure of X-irradiated larvae to immunize young lambs”. Am. J. vet. Res., 27, 16411643.Google ScholarPubMed
Urquhart, G. M., Jarrett, W. F. H., Jennings, F. W., Mcintyre, W. I.M., Mulligan, W. and Sharp, M. C. C., 1966b.— “Immunity to Haemonchus contortus infection. Relationship between age and successful vaccination with irradiated larvae”. Am. J. vet. Res. 27, 16451648.Google ScholarPubMed