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Microfluidics with ultrasound-driven bubbles

Published online by Cambridge University Press:  10 November 2006

P. MARMOTTANT
Affiliation:
Department of Science and Technology, University of Twente, P.O. Box 217, 7500AE Enschede, The Netherlands Present address: Laboratoire de Spectrométrie Physique, CNRS-Université Joseph Fourier, BP 87, F-38047 Saint Martin d'Hères, France.
J. P. RAVEN
Affiliation:
Department of Science and Technology, University of Twente, P.O. Box 217, 7500AE Enschede, The Netherlands Present address: Laboratoire de Spectrométrie Physique, CNRS-Université Joseph Fourier, BP 87, F-38047 Saint Martin d'Hères, France.
H. GARDENIERS
Affiliation:
MESA+ Research Institute, University of Twente, P.O. Box 217, 7500AE Enschede, The Netherlands
J. G. BOMER
Affiliation:
MESA+ Research Institute, University of Twente, P.O. Box 217, 7500AE Enschede, The Netherlands
S. HILGENFELDT
Affiliation:
Department of Science and Technology, University of Twente, P.O. Box 217, 7500AE Enschede, The Netherlands Present address: Engineering Sciences & Applied Mathematics and Dept. of Mechanical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.

Abstract

Microstreaming from oscillating bubbles is known to induce vigorous vortex flow. Here we show how to harness the power of bubble streaming in an experiment to achieve directed transport flow of high velocity, allowing design and manufacture of microfluidic MEMS devices. By combining oscillating bubbles with solid protrusions positioned on a patterned substrate, solid beads and lipid vesicles are guided in desired directions without microchannels. Simultaneously, the flow exerts controlled localized forces capable of opening and reclosing lipid membranes.

Type
Papers
Copyright
© 2006 Cambridge University Press

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