Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-19T01:14:06.344Z Has data issue: false hasContentIssue false
  • English
  • Français

Size for gestational age at birth according to offspring sex and gestational weight gain in underweight women

Published online by Cambridge University Press:  18 February 2019

Y. Kasuga Open the ORCID record for Y. Kasuga [Opens in a new window] ,
D. Shigemi ,
M. Tamagawa ,
T. Suzuki ,
S.-H. Kim ,
T. Higuchi ,
H. Yasunaga  and
S. Nakada
Y. Kasuga*
Affiliation:
Department of Obstetrics and Gynecology, Kawasaki Municipal Kawasaki Hospital, Kanagawa, Japan
D. Shigemi
Affiliation:
Department of Clinical Epidemiology & Health Economics, School of Public Health, The Graduate School of Medicine and Faculty of Medicine at the University of Tokyo, Tokyo, Japan
M. Tamagawa
Affiliation:
Department of Obstetrics and Gynecology, Kawasaki Municipal Kawasaki Hospital, Kanagawa, Japan
T. Suzuki
Affiliation:
Department of Obstetrics and Gynecology, Kawasaki Municipal Kawasaki Hospital, Kanagawa, Japan
S.-H. Kim
Affiliation:
Department of Obstetrics and Gynecology, Kawasaki Municipal Kawasaki Hospital, Kanagawa, Japan
T. Higuchi
Affiliation:
Department of Obstetrics and Gynecology, Kawasaki Municipal Kawasaki Hospital, Kanagawa, Japan
H. Yasunaga
Affiliation:
Department of Clinical Epidemiology & Health Economics, School of Public Health, The Graduate School of Medicine and Faculty of Medicine at the University of Tokyo, Tokyo, Japan
S. Nakada
Affiliation:
Department of Obstetrics and Gynecology, Kawasaki Municipal Kawasaki Hospital, Kanagawa, Japan
*
Address for correspondence: Y. Kasuga, Department of Obstetrics and Gynecology, Kawasaki Municipal Kawasaki Hospital, 12-1 Shinkawa-Dori, Kawasaki-ku, Kawasaki, Kanagawa 210-0013, Japan. E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Although maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) are related to fetal growth, there is a paucity of data regarding how offspring sex affects the relationship between maternal BMI in underweight mothers (pre-pregnancy BMI <18.5 kg/m2) and size for gestational age at birth. The aim of this study was to investigate the effect of offspring sex on the relationships among maternal pre-pregnancy BMI, GWG and size for gestational age at birth in Japanese underweight mothers. Records of women with full-term pregnancies who underwent perinatal care at Kawasaki Municipal Hospital (Kawasaki, Japan) between January 2013 and December 2017 were retrospectively reviewed. The study cohort included underweight (n=566) and normal-weight women (18.5 kg/m2⩽pre-pregnancy BMI<25 kg/m2; n=2671). The incidence of small for gestational age (SGA) births in the underweight group was significantly higher than that in the normal-weight group (P<0.01). Additionally, SGA incidence in the underweight group was significantly higher than that in the normal-weight group (P<0.01) in female, but not male (P=0.30) neonates. In the women with female neonates, pre-pregnancy underweight was associated with a significantly increased probability of SGA (odds ratio [OR]: 1.80; P<0.01), but inadequate GWG was not (OR: 1.38; P=0.11). In contrast, in women with male neonates, inadequate GWG was associated with a significantly increased probability of SGA (OR: 1.53; P=0.03), but not with pre-pregnancy underweight (OR: 1.30; P=0.10). In conclusion, the present results suggest that pre-pregnancy underweight is associated with SGA in female offspring but not in male offspring.

Keywords

gestational weight gainoffspring sexsmall for gestational ageunderweight
Type
Original Article
Information
Journal of Developmental Origins of Health and Disease , Volume 10 , Issue 5 , October 2019 , pp. 536 - 541
Copyright
© Cambridge University Press and the International Society for Developmental Origins of Health and Disease 2019 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Jeric, M, Roje, D, Medic, N, Strinic, T, Mestrovic, Z, Vulic, M. Maternal pre-pregnancy underweight and fetal growth in relation to institute of medicine recommendations for gestational weight gain. Early Hum Dev. 2013; 89, 277–281.CrossRefGoogle ScholarPubMed
Fujiwara, K, Aoki, S, Kurasawa, K, Okuda, M, Takahashi, T, Hirahara, F. Associations of maternal pre-pregnancy underweight with small-for-gestational-age and spontaneous preterm birth, and optimal gestational weight gain in Japanese women. J Obstet Gynaecol Res. 2014; 40, 988–994.CrossRefGoogle ScholarPubMed
Yu, Z, Han, S, Zhu, J, Sun, X, Ji, C, Guo, X. Pre-pregnancy body mass index in relation to infant birth weight and offspring overweight/obesity: a systematic review and meta-analysis. PLoS One. 2013; 8, e61627.CrossRefGoogle ScholarPubMed
Barker, DJ, Winter, PD, Osmond, C, Margetts, B, Simmonds, SJ. Weight in infancy and death from ischaemic heart disease. Lancet. 1989; 2, 577–580.CrossRefGoogle ScholarPubMed
Boney, CM, Verma, A, Tucker, R, Vohr, BR. Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics. 2005; 115, e290–e296.CrossRefGoogle ScholarPubMed
Morisaki, N, Kawachi, I, Oken, E, Fujiwara, T. Parental characteristics can explain why Japanese women give birth to the smallest infants in the United States. Paediatr Perinat Epidemiol. 2016; 30, 473–478.CrossRefGoogle ScholarPubMed
Enomoto, K, Aoki, S, Toma, R, Fujiwara, K, Sakamaki, K, Hirahara, F. Pregnancy outcomes based on pre-pregnancy body mass index in Japanese women. PLoS One. 2016; 11, e0157081.CrossRefGoogle ScholarPubMed
Melby, MK, Yamada, G, Surkan, PJ. Inadequate gestational weight gain increases risk of small-for-gestational-age term birth in girls in Japan: a population-based cohort study. Am J Hum Biol. 2016; 28, 714–720.CrossRefGoogle ScholarPubMed
Pugh, SJ, Albert, PS, Kim, S, et al. Patterns of gestational weight gain and birthweight outcomes in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Fetal Growth Studies-Singletons: a prospective study. Am J Obstet Gynecol. 2017; 217, 346 e1–e11.CrossRefGoogle ScholarPubMed
Waters, TP, Huston-Presley, L, Catalano, PM. Neonatal body composition according to the revised institute of medicine recommendations for maternal weight gain. J Clin Endocrinol Metab. 2012; 97, 3648–3654.CrossRefGoogle ScholarPubMed
Nomura, K, Kido, M, Tanabe, A, Nagashima, K, Takenoshita, S, Ando, K. Investigation of optimal weight gain during pregnancy for Japanese women. Sci Rep. 2017; 7, 2569.CrossRefGoogle ScholarPubMed
O’Tierney-Ginn, P, Presley, L, Minium, J, Hauguel deMouzon, S, Catalano, PM. Sex-specific effects of maternal anthropometrics on body composition at birth. Am J Obstet Gynecol. 2014; 211, 292 e1–292 e9.CrossRefGoogle ScholarPubMed
Sojo, L, Garcia-Patterson, A, Maria, MA, et al. Are birth weight predictors in diabetic pregnancy the same in boys and girls? Eur J Obstet Gynecol Reprod Biol. 2010; 153, 32–37.CrossRefGoogle ScholarPubMed
Mando, C, Calabrese, S, Mazzocco, MI, et al. Sex specific adaptations in placental biometry of overweight and obese women. Placenta. 2016; 38, 1–7.CrossRefGoogle ScholarPubMed
Minakami, H, Maeda, T, Fujii, T, et al. Guidelines for obstetrical practice in Japan: Japan Society of Obstetrics and Gynecology (JSOG) and Japan Association of Obstetricians and Gynecologists (JAOG) 2014 edition. J Obstet Gynaecol Res. 2014; 40, 1469–1499.CrossRefGoogle ScholarPubMed
Morisaki, N, Nagata, C, Jwa, SC, et al. Pre-pregnancy BMI-specific optimal gestational weight gain for women in Japan. J Epidemiol. 2017; 27, 492–498.CrossRefGoogle ScholarPubMed
Rasmussen, KM, Yaktine, AL, Institute of Medicine (U.S.). Committee to Reexamine IOM Pregnancy Weight Guidelines. Weight gain during pregnancy: reexamining the guidelines. 2009. National Academies Press: Washington, DC.Google Scholar
Itabashi, K, Miura, F, Uehara, R, Nakamura, Y. New Japanese neonatal anthropometric charts for gestational age at birth. Pediatr Int. 2014; 56, 702–708.CrossRefGoogle ScholarPubMed
Macdonald, EM, Natale, R, Regnault, TR, Koval, JJ, Campbell, MK. Obstetric conditions and the placental weight ratio. Placenta. 2014; 35, 582–586.CrossRefGoogle ScholarPubMed
Goldstein, RF, Abell, SK, Ranasinha, S, et al. Association of gestational weight gain with maternal and infant outcomes: a systematic review and meta-analysis. JAMA. 2017; 317, 2207–2225.CrossRefGoogle ScholarPubMed
Lampl, M, Gotsch, F, Kusanovic, JP, et al. Sex differences in fetal growth responses to maternal height and weight. Am J Hum Biol. 2010; 22, 431–443.CrossRefGoogle ScholarPubMed
Simon, L, Borrego, P, Darmaun, D, Legrand, A, Roze, JC, Chauty-Frondas, A. Effect of sex and gestational age on neonatal body composition. Br J Nutr. 2013; 109, 1105–1108.CrossRefGoogle ScholarPubMed
Murai, U, Nomura, K, Kido, M, Takeuchi, T, Sugimoto, M, Rahman, M. Pre-pregnancy body mass index as a predictor of low birth weight infants in Japan. Asia Pac J Clin Nutr. 2017; 26, 434–437.Google ScholarPubMed
Hull, HR, Dinger, MK, Knehans, AW, Thompson, DM, Fields, DA. Impact of maternal body mass index on neonate birthweight and body composition. Am J Obstet Gynecol. 2008; 198, 416 e1–416 e6.CrossRefGoogle ScholarPubMed
Badfar, G, Shohani, M, Soleymani, A, Azami, M. Maternal anemia during pregnancy and small for gestational age: a systematic review and meta-analysis. J Matern Fetal Neonatal Med. 2018; 1–7, doi:10.1080/14767058.2017.1411477.CrossRefGoogle Scholar
Wallace, JM, Horgan, GW, Bhattacharya, S. Placental weight and efficiency in relation to maternal body mass index and the risk of pregnancy complications in women delivering singleton babies. Placenta. 2012; 33, 611–618.CrossRefGoogle ScholarPubMed