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Repercussions of maternal exposure to high-fat diet on offspring feeding behavior and body composition: a systematic review

Published online by Cambridge University Press:  27 April 2020

Wenicios Ferreira Chaves ,
Isabeli Lins Pinheiro ,
Jacqueline Maria da Silva ,
Raul Manhães-de-Castro  and
Raquel da Silva Aragão Open the ORCID record for Raquel da Silva Aragão [Opens in a new window]
Wenicios Ferreira Chaves
Affiliation:
Graduate Program of Nutrition, Department of Nutrition, Universidade Federal de Pernambuco, Recife, PE50670-901, Brazil
Isabeli Lins Pinheiro
Affiliation:
Physical Education and Sports Sciences Nucleus, Universidade Federal de Pernambuco, Vitória de Santo Antão, PE55608-680, Brazil
Jacqueline Maria da Silva
Affiliation:
Graduate Program of Nutrition, Department of Nutrition, Universidade Federal de Pernambuco, Recife, PE50670-901, Brazil
Raul Manhães-de-Castro
Affiliation:
Graduate Program of Nutrition, Department of Nutrition, Universidade Federal de Pernambuco, Recife, PE50670-901, Brazil
Raquel da Silva Aragão*
Affiliation:
Graduate Program of Nutrition, Department of Nutrition, Universidade Federal de Pernambuco, Recife, PE50670-901, Brazil Physical Education and Sports Sciences Nucleus, Universidade Federal de Pernambuco, Vitória de Santo Antão, PE55608-680, Brazil Graduate Program of Nutrition, Physical Activity and Phenotypic Plasticity, Universidade Federal de Pernambuco, Vitória de Santo Antão, PE55608-680, Brazil
*
Address for correspondence: Raquel da Silva Aragão, Núcleo de Educação Física e Ciências do Esporte, Centro Acadêmico de Vitória, Universidade Federal de Pernambuco, Rua Alto do Reservatório, s/n, Bela Vista, Vitória de Santo Antão, PE55608-680, Brazil. Email: [email protected]
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Abstract

Maternal nutrition is an environmental determinant for offspring growth and development, especially in critical periods. Nutritional imbalances during these phases can promote dysregulations in food intake and feeding preference in offspring, affecting body composition. The aim of this review is to summarize and discuss the effects of maternal high-fat diet (HFD) on offspring feeding behavior and body composition. A search was performed in the PUBMED, SCOPUS, Web of Science, and LILACS databases. Inclusion criteria were studies in rodents whose mothers were submitted to HFD that assessed outcomes of food or caloric intake on offspring and food preference associated or not with body weight or body composition analysis. At the end of the search, 17 articles with the proposed characteristics were included. In these studies, 15 articles manipulated diet during pregnancy and lactation, 1 during pregnancy only, and 1 during lactation only. Maternal exposure to a HFD leads to increased food intake, increased preference for HFDs, and earlier food independence in offspring. The offspring from HFD mothers present low birthweight but become heavier into adulthood. In addition, these animals also exhibited greater fat deposition on white adipose tissue pads. In conclusion, maternal exposure to HFD may compromise parameters in feeding behavior and body composition of offspring, impairing the health from conception until adulthood.

Keywords

Feeding behaviorbody compositionhigh-fat dietperinatal periodfood intake
Type
Review
Information
Journal of Developmental Origins of Health and Disease , Volume 12 , Issue 2 , April 2021 , pp. 220 - 228
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Copyright
© Cambridge University Press and the International Society for Developmental Origins of Health and Disease 2020

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