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Simmental × Holstein crossbred: comparison of immunological traits with parental breeds during peripartum and early lactation period

Published online by Cambridge University Press:  06 November 2020

Maria Carmela Scatà ,
Francesco Grandoni ,
Vittoria Lucia Barile ,
Gennaro Catillo  and
Giovanna De Matteis
Maria Carmela Scatà*
Affiliation:
Council for Agricultural Research and Economics, CREA Research Centre for Animal Production and Aquaculture, Via Salaria 31-00015 Monterotondo (RM), Italy
Francesco Grandoni
Affiliation:
Council for Agricultural Research and Economics, CREA Research Centre for Animal Production and Aquaculture, Via Salaria 31-00015 Monterotondo (RM), Italy
Vittoria Lucia Barile
Affiliation:
Council for Agricultural Research and Economics, CREA Research Centre for Animal Production and Aquaculture, Via Salaria 31-00015 Monterotondo (RM), Italy
Gennaro Catillo
Affiliation:
Council for Agricultural Research and Economics, CREA Research Centre for Animal Production and Aquaculture, Via Salaria 31-00015 Monterotondo (RM), Italy
Giovanna De Matteis
Affiliation:
Council for Agricultural Research and Economics, CREA Research Centre for Animal Production and Aquaculture, Via Salaria 31-00015 Monterotondo (RM), Italy
*
Author for correspondence: Maria Carmela Scatà, Email: [email protected]
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Abstract

The experiment described in this research communication aimed to compare the immunological traits of Simmental (sire) × Holstein (dam) crossbred cows with the two parental breeds in the peripartum and early lactation period and to estimate the effects of heterosis for these traits. Flow cytometric evaluation of leukocyte subpopulations was assessed in 16 Crossbred (CR), 8 Holstein (HO) and 8 Simmental (SI) cows. Estimated average values of innate and adaptive immune cells showed statistically significant differences between the crossbred cows and parental breeds. Interestingly, the most relevant differences between the three groups related to adaptive immune cells. In particular, the CR cows showed a lower percentage of CD3+ T lymphocytes compared with the SI group (P < 0.0001) and the highest proportions of CD21+ B lymphocytes among the three groups (P < 0.0001). Furthermore, we found the highest positive value of heterosis for the CD21+ B lymphocytes (7.0) and the lowest negative value for CD3+ T lymphocytes (−4.8) in F1 derived population. It seems reasonable to believe that these differences could affect immune function of crossbred cows.

Keywords

Crossbreedingflow cytometryheterosisimmunological traitsperipartum period
Type
Research Article
Information
Journal of Dairy Research , Volume 87 , Issue 4 , November 2020 , pp. 424 - 428
Copyright
Copyright © The Author(s), 2020. Published by Cambridge University Press on behalf of Hannah Dairy Research Foundation

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References

Aleri, J, Hine, BC, Pyman, MF, Mansell, PD, Wales, WJ, Mallard, B and Fisher, AD (2016) Periparturient immunosuppression and strategies to improve dairy cow health during the periparturient period. Research in Veterinary Science 108, 8–17.CrossRefGoogle ScholarPubMed
Cartwright, SL, Begley, N, Schaeffer, LR, Burnside, EB and Mallard, BA (2011) Antibody and cell-mediated immune responses and survival between Holstein and Norwegian Red×Holstein Canadian calves. Journal of Dairy Science 94, 1576–1585.CrossRefGoogle Scholar
Chaplin, DD (2010) Overview of the immune response. The Journal of Allergy and Clinical Immunology 125, S3–23.10.1016/j.jaci.2009.12.980CrossRefGoogle ScholarPubMed
Falconer, DS (1960) Introduction to Quantitative Genetics. Edinburgh: Oliver and Boyd Ltd, pp. 1–140. ISBN 058244764X.Google Scholar
Heiser, A, McCarthy, A, Wedlock, N, Meier, S, Kay, L, Walker, C, Crookenden, MA, Mitchell, MD, Morgan, S, Watkins, K, Loor, JJ and Roche, JR (2015) Grazing dairy cows had decreased interferon-γ, tumor necrosis factor, and interleukin-17, and increased expression of interleukin-10 during the first week after calving. Journal of Dairy Science 98, 937–946.10.3168/jds.2014-8494CrossRefGoogle ScholarPubMed
Kimura, K, Goff, JP, Kehrli, ME JR and Harp, JA (1999) Phenotype analysis of peripheral blood mononuclear cells in periparturient dairy cows. Journal of Dairy Science 82, 315–9.CrossRefGoogle ScholarPubMed
Knob, DA, Alessio, DRM, Thaler Neto, A and Mozzaquatro, FD (2016) Reproductive performance and survival of Holstein and Holstein×Simmental crossbred cows. Tropical Animal Health and Production 48, 1409–1413.10.1007/s11250-016-1103-9CrossRefGoogle ScholarPubMed
Lopreiato, V, Minuti, A, Trimboli, F, Britti, D, Morittu, VM, Piccioli-Cappelli, F, Loor, JJ and Trevisi, E (2019a) Immunometabolic status and productive performance differences between periparturient Simmental and Holstein dairy cows in response to pegbovigrastim. Journal of Dairy Science 102, 9312–9327.10.3168/jds.2019-16323CrossRefGoogle Scholar
Lopreiato, V, Minuti, A, Morittu, VM, Britti, D, Piccioli-Cappelli, F, Loor, JJ and Trevisi, E (2019b) Short communication: inflammation, migration, and cell-cell interaction-related gene network expression in leukocytes is enhanced in Simmental compared with Holstein dairy cows after calving. Journal of Dairy Science 102, 9312–9327.10.3168/jds.2019-16323CrossRefGoogle Scholar
Meglia, GE, Johannisson, A, Agenäs, S, Holtenius, K and Persson Waller, K (2005) Effects of feeding intensity during the dry period on leukocyte and lymphocyte sub-populations, neutrophil function and health in periparturient dairy cows. The Veterinary Journal 169, 376–84.CrossRefGoogle ScholarPubMed
O'Brien, SJ and Evermann, JF (1988) Interactive influence of infectious disease and genetic diversity in natural populations. Trends in Ecology & Evolution 3, 254–259.10.1016/0169-5347(88)90058-4CrossRefGoogle ScholarPubMed
Parland, SM, Kearney, JF, Rath, M and Berry, DP (2007) Inbreeding effects on milk production, calving performance, fertility, and conformation in Irish Holstein–Friesians. Journal of Dairy Science 90, 4411–4419.10.3168/jds.2007-0227CrossRefGoogle Scholar
Stelwagen, K, Carpenter, E, Haigh, B, Hodgkinson, A and Wheeler, TT (2009) Immune components of bovine colostrum and milk. Journal of Animal Science 87(suppl.) 3–9CrossRefGoogle ScholarPubMed
Van Kampen, C and Mallard, BA (1997) Effect of peripartum stress and health on circulating bovine lymphocyte subset. Veterinary Immunology and Immunopathology 59, 79–91.CrossRefGoogle Scholar
Weber, PS, Toelboell, T, Chang, LC, Tirrell, JD, Saama, PM, Smith, GW and Burton, JL (2004) Mechanisms of glucocorticoid-induced down-regulation of neutrophil L-selectin in cattle: evidence for effects at the gene-expression level and primarily on blood neutrophils. Journal of Leukocyte Biology 75, 815–27.10.1189/jlb.1003505CrossRefGoogle ScholarPubMed
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