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Lack of evidence of IgE allergic sensitisation from working with lactic acid bacteria in the dairy foods industry

Published online by Cambridge University Press:  18 June 2018

Coralie Barrera ,
Gabriel Reboux ,
Audrey Laboissière ,
Laurence Millon  and
Anne Oppliger
Coralie Barrera
Affiliation:
UMR/CNRS 6249 Chrono-Environnement, University of Bourgogne Franche-Comté, UFR Sciences médicales et pharmaceutiques, 19 rue Ambroise Paré, 25030 Besançon, France Department of Parasitology-Mycology, University Hospital, 2Bd Fleming, 25030 Besançon, France
Gabriel Reboux*
Affiliation:
UMR/CNRS 6249 Chrono-Environnement, University of Bourgogne Franche-Comté, UFR Sciences médicales et pharmaceutiques, 19 rue Ambroise Paré, 25030 Besançon, France Department of Parasitology-Mycology, University Hospital, 2Bd Fleming, 25030 Besançon, France
Audrey Laboissière
Affiliation:
UMR/CNRS 6249 Chrono-Environnement, University of Bourgogne Franche-Comté, UFR Sciences médicales et pharmaceutiques, 19 rue Ambroise Paré, 25030 Besançon, France Department of Parasitology-Mycology, University Hospital, 2Bd Fleming, 25030 Besançon, France
Laurence Millon
Affiliation:
UMR/CNRS 6249 Chrono-Environnement, University of Bourgogne Franche-Comté, UFR Sciences médicales et pharmaceutiques, 19 rue Ambroise Paré, 25030 Besançon, France Department of Parasitology-Mycology, University Hospital, 2Bd Fleming, 25030 Besançon, France
Anne Oppliger
Affiliation:
Institute of Work and Health, University of Lausanne, route de la Corniche 2, 1066 Epalinges-Lausanne, Switzerland
*
*For correspondence; e-mail: [email protected]
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Abstract

This research communication aimed to evaluate the level of immunoglobulin E from lactic acid bacteria (LAB) that are used in dairy industries. Previous studies have demonstrated that workers report symptoms of irritation and are frequently IgG-sensitised to LAB. Workers (n = 44) from a probiotic production unity and the control lab were seen by a medical practitioner and responded to an occupational questionnaire. Specific IgE by the DELFIA® technique against 6 strains of LAB were measured on 44 exposed workers and 31 controls sera. Levels of specific IgE were low and no difference was observed between the two groups. This lack of IgE response could be explained by a healthy worker effect, an efficient implementation of personal protective equipment or by an absence of allergic mechanisms to account for the self-reported irritative symptoms. Despite the high concentrations of LAB, preventive measures are effective enough to guarantee no allergic effect and to prevent other adverse health effects. The implementation of preventive measures to avoid or reduce exposure to dust of LAB, and more generally to milk powder, is recommended in all dairy industry.

Type
Research Article
Information
Journal of Dairy Research , Volume 85 , Issue 3 , August 2018 , pp. 355 - 357
Copyright
Copyright © Hannah Dairy Research Foundation 2018 

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References

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