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Hormone variations in serum and milk of buffaloes (Bubalus bubalis) as potential indicators of treatment with recombinant bovine somatotropin

Published online by Cambridge University Press:  16 August 2011

Lorenzo Castigliego ,
Xiao Ning Li ,
Andrea Armani ,
Goffredo Grifoni ,
Carlo Boselli ,
Remo Rosati ,
Daniela Gianfaldoni  and
Alessandra Guidi
Lorenzo Castigliego*
Affiliation:
Department of Animal Pathology, Prophylaxis and Food Hygiene, University of Pisa, Via delle Piagge 2-56124, Pisa, Italy
Xiao Ning Li
Affiliation:
Department of Animal Science and Technology, University of Guangxi, Daxue Road 100, Nanning, People's Republic of China
Andrea Armani
Affiliation:
Department of Animal Pathology, Prophylaxis and Food Hygiene, University of Pisa, Via delle Piagge 2-56124, Pisa, Italy
Goffredo Grifoni
Affiliation:
Experimental Zooprophylactic Institute of Lazio and Tuscany, Via Appia Nuova 1411-00178, Rome, Italy
Carlo Boselli
Affiliation:
Experimental Zooprophylactic Institute of Lazio and Tuscany, Via Appia Nuova 1411-00178, Rome, Italy
Remo Rosati
Affiliation:
Experimental Zooprophylactic Institute of Lazio and Tuscany, Via Appia Nuova 1411-00178, Rome, Italy
Daniela Gianfaldoni
Affiliation:
Department of Animal Pathology, Prophylaxis and Food Hygiene, University of Pisa, Via delle Piagge 2-56124, Pisa, Italy
Alessandra Guidi
Affiliation:
Department of Animal Pathology, Prophylaxis and Food Hygiene, University of Pisa, Via delle Piagge 2-56124, Pisa, Italy
*
*For correspondence: [email protected]
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Abstract

Recombinant bovine somatotropin (rbST) is used to increase milk yield in cows, but it has been forbidden in some countries and in the EU. However, rbST misuse represents a concern in both bovine and buffalo dairy production. A number of studies on rbST treatment have been performed on bovines, but there are few data on buffaloes. In this study, we treated eight lactating buffaloes with biweekly injections of a slow-release formulation of rbST, for five cycles of administration, and analysed total ST and insulin-like growth factor 1 (IGF-1) variations in serum and IGF-1 in milk. The aim was to assess their power as potential indicators of rbST-treatment. Blood was collected on days 2, 5, 9 and 14 of each cycle, and milk on days 2, 9 and 14 of cycles 2 and 5. Results showed an extraordinary increase in ST levels on day 2 in treated animals, followed by a rapid decrease over the following days, while a significant increase in IGF-1 was observed both in serum and in milk throughout most of each cycle. These results suggest that serum ST levels are a good indicator of treatment. However, the rapid decrease after the peak limits the useful period of sample collection.

Keywords

Recombinant bovine somatotropinbuffalomilkIGF-1
Type
Research Article
Information
Journal of Dairy Research , Volume 78 , Issue 4 , November 2011 , pp. 412 - 420
Copyright
Copyright © Proprietors of Journal of Dairy Research 2011

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